Endothelial dysfunction and platelet hyperactivity in type 2 diabetes mellitus: molecular insights and therapeutic strategies

R Kaur, M Kaur, J Singh - Cardiovascular diabetology, 2018 - Springer
The incidence and prevalence of diabetes mellitus is rapidly increasing worldwide at an
alarming rate. Type 2 diabetes mellitus (T2DM) is the most prevalent form of diabetes …

Impact of diabetes on cardiovascular disease: an update

ASM Matheus, LRM Tannus, RA Cobas… - International journal …, 2013 - Wiley Online Library
Cardiovascular diseases are the most prevalent cause of morbidity and mortality among
patients with type 1 or type 2 diabetes. The proposed mechanisms that can link accelerated …

Diabetes mellitus and thrombosis

N Vazzana, P Ranalli, C Cuccurullo, G Davì - Thrombosis research, 2012 - Elsevier
Atherothrombosis is the leading cause of morbidity and mortality in patients with diabetes
mellitus. Several mechanisms contribute to the diabetic prothrombotic state, including …

Inflammatory status and insulin resistance

RF Grimble - Current Opinion in Clinical Nutrition & Metabolic …, 2002 - journals.lww.com
Recent studies on diseases which involve insulin insensitivity (eg obesity, type 2 diabetes
and atherosclerosis) also show increased cytokine production and markers of inflammation …

Spectrum and prevalence of atherogenic risk factors in 27,358 children, adolescents, and young adults with type 1 diabetes: cross-sectional data from the German …

KO Schwab, J Doerfer, W Hecker… - Diabetes …, 2006 - Am Diabetes Assoc
OBJECTIVE—The aim of this data analysis was to ascertain the type and prevalence rate as
well as age and sex distribution of cardiovascular risk factors in type 1 diabetic patients up to …

The change of serum tumor necrosis factor alpha in patients with type 1 diabetes mellitus: A systematic review and meta-analysis

Y Qiao, Y Chen, Y Pan, F Tian, Y Xu, X Zhang, H Zhao - PloS one, 2017 - journals.plos.org
Objective The aim of this study was used meta-analysis to investigate changes of serum
tumor necrosis factor-alpha (TNF-α) in patients with type 1 diabetes mellitus (T1DM) …

Obesity, metabolic syndrome, and cardiovascular disease

Y Aggoun - Pediatric research, 2007 - nature.com
Early childhood overweight and obesity have alarmingly increased over the years.
Adulthood obesity is a well demonstrated significant independent predictor of cardiovascular …

Microparticles as new markers of cardiovascular risk in diabetes and beyond

F Santilli, M Marchisio, P Lanuti… - Thrombosis and …, 2016 - thieme-connect.com
The term microparticle (MP) identifies a heterogeneous population of vesicles playing a
relevant role in the pathogenesis of vascular diseases, cancer and metabolic diseases such …

[HTML][HTML] Diabetes and hypertension: pivotal involvement of purinergic signaling

KP Reichert, MFV Castro, CE Assmann… - Biomedicine & …, 2021 - Elsevier
Diabetes mellitus (DM) and hypertension are highly prevalent worldwide health problems
and frequently associated with severe clinical complications, such as diabetic …

[HTML][HTML] Endothelial dysfunction as a predictor of cardiovascular disease in type 1 diabetes

MC Bertoluci, GV Cé, AMV da Silva… - World journal of …, 2015 - ncbi.nlm.nih.gov
Macro and microvascular disease are the main cause of morbi-mortality in type 1 diabetes
(T1DM). Although there is a clear association between endothelial dysfunction and …