Advances in the development of nonpeptide small molecules targeting ghrelin receptor

G Giorgioni, F Del Bello, W Quaglia… - Journal of Medicinal …, 2022 - ACS Publications
Ghrelin is an octanoylated peptide acting by the activation of the growth hormone
secretagogue receptor, namely, GHS-R1a. The involvement of ghrelin in several …

Role of the CB2 Cannabinoid Receptor in the Regulation of Food Intake: A Systematic Review

LM Rodríguez-Serrano… - International Journal of …, 2023 - mdpi.com
The CB2 cannabinoid receptor has been found in brain areas that are part of the reward
system and has been shown to play a role in food intake regulation. Herein, we conducted a …

Impaired Ghrelin Signaling Does Not Lead to Alterations of Anxiety-like Behaviors in Adult Mice Chronically Exposed to THC during Adolescence

M Sestan-Pesa, M Shanabrough, TL Horvath… - Biomedicines, 2023 - mdpi.com
As marijuana use during adolescence has been increasing, the need to understand the
effects of its long-term use becomes crucial. Previous research suggested that marijuana …

Ghrelin and Cannabinoid Functional Interactions Mediated by Ghrelin/CB1 Receptor Heteromers That Are Upregulated in the Striatum From Offspring of Mice Under …

A Lillo, J Lillo, I Raïch, C Miralpeix, F Dosrius… - Frontiers in Cellular …, 2021 - frontiersin.org
There is evidence of ghrelinergic-cannabinoidergic interactions in the central nervous
system (CNS) that may impact on the plasticity of reward circuits. The aim of this article was …

Untersuchungen zur β-Arrestin 2 Rekrutierung und lateralen Mobilität von 5HT1a-Rezeptoren allein sowie unter dem Einfluss koexprimierter 5HT2a- bzw. 5HT72 …

E Weitkemper - 2024 - bonndoc.ulb.uni-bonn.de
Dem 5HT 1a-Rezeptor (5HT 1a R) wird in der Familie der Serotoninrezeptoren besondere
Aufmerksamkeit zuteil, da er eine Schlüsselrolle bei der Regulation des Serotonin-Systems …