Biocompatibility evolves: phenomenology to toxicology to regeneration

L Crawford, M Wyatt, J Bryers… - Advanced healthcare …, 2021 - Wiley Online Library
The word “biocompatibility,” is inconsistent with the observations of healing for so‐called
biocompatible biomaterials. The vast majority of the millions of medical implants in humans …

[HTML][HTML] Emerging strategies to bypass transplant rejection via biomaterial-assisted immunoengineering: Insights from islets and beyond

S Abbaszadeh, V Nosrati-Siahmazgi, K Musaie… - Advanced Drug Delivery …, 2023 - Elsevier
Novel transplantation techniques are currently under development to preserve the function
of impaired tissues or organs. While current technologies can enhance the survival of …

Biomaterial strategies for selective immune tolerance: advances and gaps

ST Carey, C Bridgeman, CM Jewell - Advanced Science, 2023 - Wiley Online Library
Autoimmunity and allergies affect a large number of people across the globe. Current
approaches to these diseases target cell types and pathways that drive disease, but these …

Translation of cell therapies to treat autoimmune disorders

JM Mehta, SC Hiremath, C Chilimba, A Ghasemi… - Advanced Drug Delivery …, 2024 - Elsevier
Autoimmune diseases are a diverse and complex set of chronic disorders with a substantial
impact on patient quality of life and a significant global healthcare burden. Current …

Unlocking Transplant Tolerance with Biomaterials

JPA Pham, MM Coronel - Advanced Healthcare Materials, 2024 - Wiley Online Library
For patients suffering from organ failure due to injury or autoimmune disease, allogeneic
organ transplantation with chronic immunosuppression is considered the gold standard in …

Engineered collagen polymeric materials create noninflammatory regenerative microenvironments that avoid classical foreign body responses

RA Morrison, S Brookes, TJ Puls, A Cox, H Gao… - Biomaterials …, 2023 - pubs.rsc.org
The efficacy and longevity of medical implants and devices is largely determined by the host
immune response, which extends along a continuum from pro-inflammatory/pro-fibrotic to …

Dissecting regulatory T cell expansion using polymer microparticles presenting defined ratios of self-antigen and regulatory cues

CJ Bridgeman, SA Shah, RS Oakes… - … in Bioengineering and …, 2023 - frontiersin.org
Biomaterials allow for the precision control over the combination and release of cargo
needed to engineer cell outcomes. These capabilities are particularly attractive as new …

New therapeutic approaches for allergy: A review of cell therapy and bio-or nano-material-based strategies

JL Paris, P de la Torre, AI Flores - Pharmaceutics, 2021 - mdpi.com
Allergy constitutes a major health issue due to its large prevalence. The established
therapeutic approaches (allergen avoidance, antihistamines, and corticosteroids) do not …

Nanoparticle-based tolerogenic vaccines for the treatment of autoimmune diseases: a review

TL Nguyen, J Kim - ACS Applied Nano Materials, 2022 - ACS Publications
Current treatments for autoimmune diseases can only ameliorate the symptoms of the
disease and may cause immunocompromised or opportunistic diseases. Recent advances …

Generation of Immune Tolerance with Combined Pharmacological Agents

CJ Genito - 2021 - search.proquest.com
The incidence of autoimmune disease is increasing worldwide. Current treatments for
autoimmune disease are often life-long and associated with general immunosuppression …