Identification of potential human beta-secretase 1 inhibitors by hierarchical virtual screening and molecular dynamics

MR do Bomfim, DB Barbosa… - Journal of …, 2023 - Taylor & Francis
Alzheimer's disease (AD) is a neurodegenerative pathology responsible for 70% of
dementia cases worldwide. Despite its relevance, the few drugs available for the treatment …

Identification of Lutzomyia longipalpis Odorant Binding Protein Modulators by Comparative Modeling, Hierarchical Virtual Screening, and Molecular Dynamics

IB Santana, FHA Leite… - Journal of Chemistry, 2018 - Wiley Online Library
Visceral leishmaniasis (VL) is the second most important vector‐borne disease in the world.
It is transmitted by Lutzomyia longipalpis in America; therefore, controlling the vector is …

Identification of potential modulator of Anopheles gambiae odorant binding protein 1 by hierarchical virtual screening and molecular dynamics

MR do Bomfim, JSC Araújo, WJC Macêdo… - Journal of …, 2021 - Taylor & Francis
Malaria is a protozoan infection transmitted by the bite of the infected female mosquito
belonging to the genus Anopheles spp., which causes more than 445 million annual deaths …

Investigação sobre o efeito repelente dos óleos naturais de citronela e eucalipto-limão eo papel de receptores ionotrópicos na identificação de moléculas repelentes …

ISD Canedo - 2020 - arca.fiocruz.br
Os repelentes são utilizados há décadas para a proteção individual contra picadas de
insetos de importância médica. Ainda assim, pouco se sabe sobre os mecanismos …