Current drugs to treat infections with herpes simplex viruses-1 and-2

LA Sadowski, R Upadhyay, ZW Greeley, BJ Margulies - Viruses, 2021 - mdpi.com
Herpes simplex viruses-1 and-2 (HSV-1 and-2) are two of the three human
alphaherpesviruses that cause infections worldwide. Since both viruses can be acquired in …

Resistance of herpes simplex viruses to nucleoside analogues: mechanisms, prevalence, and management

J Piret, G Boivin - Antimicrobial agents and chemotherapy, 2011 - Am Soc Microbiol
Herpes simplex viruses (HSV) type 1 and type 2 are responsible for recurrent orolabial and
genital infections. The standard therapy for the management of HSV infections includes …

Antiviral drug resistance of human cytomegalovirus

NS Lurain, S Chou - Clinical microbiology reviews, 2010 - Am Soc Microbiol
The study of human cytomegalovirus (HCMV) antiviral drug resistance has enhanced
knowledge of the virological targets and the mechanisms of antiviral activity. The currently …

Advances and perspectives in the management of varicella-zoster virus infections

G Andrei, R Snoeck - Molecules, 2021 - mdpi.com
Varicella-zoster virus (VZV), a common and ubiquitous human-restricted pathogen, causes a
primary infection (varicella or chickenpox) followed by establishment of latency in sensory …

New strategies against drug resistance to herpes simplex virus

YC Jiang, H Feng, YC Lin, XR Guo - International journal of oral …, 2016 - nature.com
Herpes simplex virus (HSV), a member of the Herpesviridae family, is a significant human
pathogen that results in mucocutaneous lesions in the oral cavity or genital infections …

[HTML][HTML] CMV: prevention, diagnosis and therapy

CN Kotton - American Journal of Transplantation, 2013 - Elsevier
Cytomegalovirus (CMV) is the most common infection after organ transplantation and has a
major impact on morbidity, mortality and graft survival. Optimal prevention, diagnosis and …

Rational approaches to improving selectivity in drug design

DJ Huggins, W Sherman, B Tidor - Journal of medicinal chemistry, 2012 - ACS Publications
Appropriate tuning of binding selectivity is a primary objective in the discovery and
optimization of a compound on the path toward developing a drug. The environment in …

International consensus guidelines on the management of cytomegalovirus in solid organ transplantation

CN Kotton, D Kumar, AM Caliendo, A Åsberg… - …, 2010 - journals.lww.com
Cytomegalovirus (CMV) remains one of the most common infections after solid organ
transplantation, resulting in significant morbidity, graft loss, and occasional mortality …

Infectious diseases in allogeneic haematopoietic stem cell transplantation: prevention and prophylaxis strategy guidelines 2016

AJ Ullmann, M Schmidt-Hieber, H Bertz, WJ Heinz… - Annals of …, 2016 - Springer
Infectious complications after allogeneic haematopoietic stem cell transplantation (allo-HCT)
remain a clinical challenge. This is a guideline provided by the AGIHO (Infectious Diseases …

Update on human herpesvirus 6 biology, clinical features, and therapy

L De Bolle, L Naesens, E De Clercq - Clinical microbiology …, 2005 - Am Soc Microbiol
SUMMARY Human herpesvirus 6 (HHV-6) is a betaherpesvirus that is closely related to
human cytomegalovirus. It was discovered in 1986, and HHV-6 literature has expanded …