Epstein-Barr virus (EBV) is a ubiquitous, oncogenic virus that is associated with a number of
different human malignancies as well as autoimmune disorders. The expression of EBV viral …

Interferons are a group of immunomodulatory substances produced by the human immune
system in response to the presence of pathogens, especially during viral and bacterial …

Interferon-beta (IFN-β) for Multiple Sclerosis (MS) is turning 30. The COVID-19 pandemic
rejuvenated the interest in interferon biology in health and disease, opening translational …

Epstein-Barr virus (EBV) is a double-stranded DNA virus of the Herpesviridae family. This
virus preferentially infects human primary B cells and persists in the human B cell …

Immediately after entry into host cells, viruses are sensed by the innate immune system,
leading to the activation of innate antiviral effector mechanisms including the type I interferon …

Background Viruses must adapt to the environment of their host cells to establish infection
and persist. Diverse mammalian cells, including virus-infected cells, release extracellular …

Some lytic proteins encoded by Epstein-Barr virus (EBV) suppress host interferon (IFN)
signaling to facilitate viral replication. In this study, we sought to identify and characterize …

Epstein-Barr virus (EBV) persistently infects 95% of adults worldwide and is associated with
multiple human lymphomas that express characteristic EBV latency programs used by the …

Human herpesvirus 8 (HHV-8) encodes four viral interferon regulatory factors (vIRFs) that
target cellular IRFs and/or other innate-immune and stress signaling regulators and …

Background Accumulating evidence has revealed that the prevalence of Coronavirus 2019
(COVID-19) was significantly higher in patients with primary Sjogren's syndrome (pSS) …