The biology, function, and biomedical applications of exosomes
BACKGROUND All cells, prokaryotes and eukaryotes, release extracellular vesicles (EVs)
as part of their normal physiology and during acquired abnormalities. EVs can be broadly …
as part of their normal physiology and during acquired abnormalities. EVs can be broadly …
Emerging prospects of exosomes for cancer treatment: from conventional therapy to immunotherapy
Exosomes are a class of extracellular vesicles of around 100 nm in diameter that are
secreted by most cells and contain various bioactive molecules reflecting their cellular origin …
secreted by most cells and contain various bioactive molecules reflecting their cellular origin …
[HTML][HTML] Reassessment of exosome composition
The heterogeneity of small extracellular vesicles and presence of non-vesicular extracellular
matter have led to debate about contents and functional properties of exosomes. Here, we …
matter have led to debate about contents and functional properties of exosomes. Here, we …
Chemotherapy elicits pro-metastatic extracellular vesicles in breast cancer models
Cytotoxic chemotherapy is an effective treatment for invasive breast cancer. However,
experimental studies in mice also suggest that chemotherapy has pro-metastatic effects …
experimental studies in mice also suggest that chemotherapy has pro-metastatic effects …
Mechanisms associated with biogenesis of exosomes in cancer
KM McAndrews, R Kalluri - Molecular cancer, 2019 - Springer
Intercellular communication between cellular compartments within the tumor and at distant
sites is critical for the development and progression of cancer. Exosomes have emerged as …
sites is critical for the development and progression of cancer. Exosomes have emerged as …
Selection of Fluorescent, Bioluminescent, and Radioactive Tracers to Accurately Reflect Extracellular Vesicle Biodistribution in Vivo
E Lázaro-Ibáñez, FN Faruqu, AF Saleh, AM Silva… - ACS …, 2021 - ACS Publications
The ability to track extracellular vesicles (EVs) in vivo without influencing their biodistribution
is a key requirement for their successful development as drug delivery vehicles and …
is a key requirement for their successful development as drug delivery vehicles and …
Current knowledge and future perspectives on mesenchymal stem cell-derived exosomes as a new therapeutic agent
Mesenchymal stem cells (MSCs) are on the cusp of regenerative medicine due to their
differentiation capacity, favorable culture conditions, ability to be manipulated in vitro, and …
differentiation capacity, favorable culture conditions, ability to be manipulated in vitro, and …
A comprehensive review on factors influences biogenesis, functions, therapeutic and clinical implications of exosomes
S Gurunathan, MH Kang, JH Kim - International journal of …, 2021 - Taylor & Francis
Exosomes are nanoscale-sized membrane vesicles secreted by almost all cell types into the
extracellular environment upon fusion of multivesicular bodies and plasma membrane …
extracellular environment upon fusion of multivesicular bodies and plasma membrane …
DNA in extracellular vesicles: biological and clinical aspects
J Elzanowska, C Semira, B Costa‐Silva - Molecular Oncology, 2021 - Wiley Online Library
The study of extracellular vesicles (EVs), especially in the liquid biopsy field, has rapidly
evolved in recent years. However, most EV studies have focused on RNA or protein content …
evolved in recent years. However, most EV studies have focused on RNA or protein content …
Extracellular signals regulate the biogenesis of extracellular vesicles
Y Jin, L Ma, W Zhang, W Yang, Q Feng, H Wang - Biological Research, 2022 - Springer
Extracellular vesicles (EVs) are naturally released membrane vesicles that act as carriers of
proteins and RNAs for intercellular communication. With various biomolecules and specific …
proteins and RNAs for intercellular communication. With various biomolecules and specific …