Current developments in LC-MS for pharmaceutical analysis

M Beccaria, D Cabooter - Analyst, 2020 - pubs.rsc.org
Liquid chromatography (LC) based techniques in combination with mass spectrometry (MS)
detection have had a large impact on the development of new pharmaceuticals in the past …

Recent advances and applications in LC-HRMS for food and plant natural products: A critical review

C Aydoğan - Analytical and Bioanalytical Chemistry, 2020 - Springer
In the last decade, interest in food and plant natural products (FPNPs) has been growing
due to their medical applications. Liquid chromatography-high-resolution mass spectrometry …

Advances and innovations in liquid chromatography stationary phase supports

K Broeckhoven, G Desmet - Analytical Chemistry, 2020 - ACS Publications
The continuous evolution of stationary phase supports over the past decades have allowed
a vast increase the separation performance in liquid chromatography. As in any …

Picoflow liquid chromatography–mass spectrometry for ultrasensitive bottom-up proteomics using 2-μm-id open tubular columns

P Xiang, Y Zhu, Y Yang, Z Zhao, SM Williams… - Analytical …, 2020 - ACS Publications
In many areas of application, key objectives of chemical separation and analysis are to
minimize the sample quantity while maximizing the chemical information obtained …

Emerging developments in separation techniques and analysis of chiral pharmaceuticals

S Al-Sulaimi, R Kushwah, M Abdullah Alsibani… - Molecules, 2023 - mdpi.com
Chiral separation, the process of isolating enantiomers from a racemic mixture, holds
paramount importance in diverse scientific disciplines. Using chiral separation methods like …

Miniaturization of liquid chromatography coupled to mass spectrometry: 1. Current trends on miniaturized LC columns

K Mejia-Carmona, JS da Silva Burato… - TrAC Trends in …, 2020 - Elsevier
Over the last decade, the use of miniaturized columns in liquid chromatography (LC) has
seen intense growth in a wide range of research areas. This report brings an overview of the …

Miniaturized LC in molecular omics

C Aydoğan, F Rigano, LK Krcmova… - Analytical …, 2020 - ACS Publications
Miniaturized LC has evolved at an exponential rate over the last 50 years. In the past
decade, it has received considerable attention in the field of bioanalytical separation science …

Theoretical computation of the band broadening in micro-pillar array columns

A Moussa, B Huygens, C Venditti, A Adrover… - … of Chromatography A, 2024 - Elsevier
We have investigated the possibility to establish a theoretical plate height expression for the
band broadening in the most widely used micro-pillar array column format, ie, a cylindrical …

Wavelet transforms in separation science for denoising and peak overlap detection

MF Wahab, TC O'Haver - Journal of separation science, 2020 - Wiley Online Library
Wavelet transform is a versatile time‐frequency analysis technique, which allows
localization of useful signals in time or space and separates them from noise. The detector …

[HTML][HTML] Chemical vapour deposition in narrow capillaries: Electro-osmotic flow control in capillary electrophoresis

MA Atia, P Smejkal, V Gupta, PR Haddad… - Analytica Chimica …, 2023 - Elsevier
Background In capillary electrophoresis (CE), the inner surface of fused-silica capillaries is
commonly covalently modified with liquid silanes to control electroosmotic flow (EOF). This …