[HTML][HTML] Tapinarof validates the aryl hydrocarbon receptor as a therapeutic target: A clinical review
JI Silverberg, M Boguniewicz, FJ Quintana… - Journal of Allergy and …, 2024 - Elsevier
The aryl hydrocarbon receptor (AhR) is a ligand-dependent transcription factor that has wide-
ranging roles, including regulation of inflammation and homeostasis. AhR is not a cell …
ranging roles, including regulation of inflammation and homeostasis. AhR is not a cell …
Tapinarof cream for the topical treatment of plaque psoriasis in adults
K Prieto, JQ Duong, SR Feldman - Expert Review of Clinical …, 2024 - Taylor & Francis
Introduction Plaque psoriasis, a chronic immune-mediated skin disorder, is characterized by
well-demarcated erythematous plaques with silvery scales. This condition stems from …
well-demarcated erythematous plaques with silvery scales. This condition stems from …
Targeting the aryl hydrocarbon receptor as a strategy to expand the therapeutic armamentarium in atopic dermatitis
LF Eichenfield, JI Silverberg, AA Hebert… - Journal of …, 2024 - Taylor & Francis
Atopic dermatitis (AD) is an intensely pruritic, chronic, relapsing, inflammatory skin disease
that commonly presents in early childhood, but also affects adults, and severely impacts the …
that commonly presents in early childhood, but also affects adults, and severely impacts the …
[HTML][HTML] Modulation of Aryl Hydrocarbon Receptor Can Be a Strategy to Improve Epidermal Barrier Function by Increasing Glucosylceramide Synthesis
K Park, Y Uchida - Journal of Investigative Dermatology, 2023 - Elsevier
A recent study by the team of Thomas Sutter (University of Memphis, Memphis, TN) reveals
that activation of the AhR promotes the transcription of glucosylceramide synthase and …
that activation of the AhR promotes the transcription of glucosylceramide synthase and …