Precision medicine in type 1 diabetes

ALJ Carr, C Evans-Molina, RA Oram - Diabetologia, 2022 - Springer
First envisioned by early diabetes clinicians, a person-centred approach to care was an
aspirational goal that aimed to match insulin therapy to each individual's unique …

Peptides as therapeutic agents: challenges and opportunities in the green transition era

G Rossino, E Marchese, G Galli, F Verde, M Finizio… - Molecules, 2023 - mdpi.com
Peptides are at the cutting edge of contemporary research for new potent, selective, and
safe therapeutical agents. Their rise has reshaped the pharmaceutical landscape, providing …

[图书][B] A guide to online pharmacy education: Teaching strategies and assessment methods

Y Al-Worafi - 2022 - taylorfrancis.com
This book describes in detail the various teaching strategies and assessment methods used
in pharmacy education. Included in the text is both the advantages and disadvantages of …

Identification of potent antimicrobial peptides via a machine-learning pipeline that mines the entire space of peptide sequences

J Huang, Y Xu, Y Xue, Y Huang, X Li, X Chen… - Nature Biomedical …, 2023 - nature.com
Systematically identifying functional peptides is difficult owing to the vast combinatorial
space of peptide sequences. Here we report a machine-learning pipeline that mines the …

Human hypoimmune primary pancreatic islets avoid rejection and autoimmunity and alleviate diabetes in allogeneic humanized mice

X Hu, C Gattis, AG Olroyd, AM Friera, K White… - Science translational …, 2023 - science.org
Transplantation of allogeneic pancreatic donor islets has successfully been performed in
selected patients with difficult-to-control insulin-dependent diabetes and impaired …

Multivalent insulin receptor activation using insulin–DNA origami nanostructures

J Spratt, JM Dias, C Kolonelou, G Kiriako… - Nature …, 2024 - nature.com
Insulin binds the insulin receptor (IR) and regulates anabolic processes in target tissues.
Impaired IR signalling is associated with multiple diseases, including diabetes, cancer and …

Closed-loop diabetes minipatch based on a biosensor and an electroosmotic pump on hollow biodegradable microneedles

X Luo, Q Yu, Y Liu, W Gai, L Ye, L Yang, Y Cui - ACS sensors, 2022 - ACS Publications
Developing a miniaturized, low-cost, and smart closed-loop system for diabetes could
significantly improve life quality and benefit millions of people. Conventional closed-loop …

Fluorescence‐Amplified Origami Microneedle Device for Quantitatively Monitoring Blood Glucose

X Li, X Xu, K Wang, Y Chen, Y Zhang, Q Si… - Advanced …, 2023 - Wiley Online Library
Exploration of clinically acceptable blood glucose monitors has been engaging in the past
decades, yet the ability to quantitatively detect blood glucose in a painless, accurate, and …

Disease-modifying therapies and features linked to treatment response in type 1 diabetes prevention: a systematic review

JL Felton, KJ Griffin, RA Oram, C Speake… - Communications …, 2023 - nature.com
Abstract Background Type 1 diabetes (T1D) results from immune-mediated destruction of
insulin-producing beta cells. Prevention efforts have focused on immune modulation and …

[HTML][HTML] Overview of artificial intelligence–driven wearable devices for diabetes: scoping review

A Ahmed, S Aziz, A Abd-Alrazaq, F Farooq… - Journal of Medical …, 2022 - jmir.org
Background Prevalence of diabetes has steadily increased over the last few decades with
1.5 million deaths reported in 2012 alone. Traditionally, analyzing patients with diabetes has …