Current diagnostic and therapeutic approaches for severe acute respiratory syndrome coronavirus-2 (SARS-COV-2) and the role of nanomaterial-based theragnosis …

B Zhang, Q Wu, L Yin, J Zhang, W Gao… - Nanotechnology …, 2023 - degruyter.com
COVID-19 was the most devastating pandemic since the Spanish Flu of 1918, affecting 700
million individuals and causing 6.8 million fatalities globally. COVID-19 vaccines are …

Characterization of cancer-driving nucleotides (CDNs) across genes, cancer types, and patients

L Zhang, T Deng, Z Liufu, X Chen, S Wu, X Liu, C Shi… - eLife, 2024 - elifesciences.org
A central goal of cancer genomics is to identify, in each patient, all the cancer-driving
mutations. Among them, point mutations are referred to as cancer-driving nucleotides …

Homo-harringtonine (HHT) is highly effective against SARS-CoV-2-A potential first-line defense in future coronavirus epidemics

HJ Wen, HJ Ma, GX Zhong, A Ding… - National Science …, 2024 - academic.oup.com
As COVID-19 is the third coronavirus epidemic in this century, it would be desirable to have
a treatment scheme in anticipation of a fourth one. We here present a scheme that could …

The paradox of extremely fast evolution driven by genetic drift in multi-copy gene systems

X Wang, Y Ruan, L Zhang, X Chen, Z Shi, H Wang… - bioRxiv, 2023 - biorxiv.org
Genetic drift should be any random forces that change gene frequency stochastically. While
the conventions including the WF (Wright-Fisher) model are about sampling errors between …

On the discovered cancer driving nucleotides (CDNs)–distributions across genes, cancer types and patients

L Zhang, T Deng, Z Liufu, X Chen, S Wu, X Liu, C Shi… - bioRxiv, 2024 - biorxiv.org
A central goal of cancer genomics is to identify, in each patient, all the cancer driving
mutations. Among them, point mutations are referred to as Cancer Driving Nucleotides …

The Generalized Haldane (GH) model tracking population size changes and resolving paradoxes of genetic drift

Y Ruan, X Wang, M Hou, L Huang, W Diao, M Tracy… - bioRxiv, 2024 - biorxiv.org
Population genetic models, such as the Wright-Fisher (WF) model, track relative gene
frequencies. The absolute gene copy number, or population size (N), is supplied externally …

[PDF][PDF] Four Years Later, Is It Already Known The Origin Of SARS-Cov-2

JL Domingo - J Comm Med and Pub Health Rep, 2024 - acquaintpublications.com
Introduction: Although the quantity of scientific information about COVID-19 and SARS-CoV-
2 (the coronavirus responsible for the COVID-19 pandemic) is currently enormous, covering …