Measuring biological aging in humans: A quest

L Ferrucci, M Gonzalez‐Freire, E Fabbri… - Aging cell, 2020 - Wiley Online Library
The global population of individuals over the age of 65 is growing at an unprecedented rate
and is expected to reach 1.6 billion by 2050. Most older individuals are affected by multiple …

Advances in development of new treatment for leishmaniasis

JPB de Menezes, CES Guedes… - BioMed research …, 2015 - Wiley Online Library
Leishmaniasis is a neglected infectious disease caused by several different species of
protozoan parasites of the genus Leishmania. Current strategies to control this disease are …

Updating the MISEV minimal requirements for extracellular vesicle studies: building bridges to reproducibility

KW Witwer, C Soekmadji, AF Hill… - Journal of …, 2017 - Taylor & Francis
An editorial describing “minimal experimental requirements for definition of extracellular
vesicles (EVs)”, or more simply “minimal information for studies of EVs (MISEV)” was …

Anticancer activity of biogenerated silver nanoparticles: an integrated proteomic investigation

M Buttacavoli, NN Albanese, G Di Cara, R Alduina… - …, 2017 - pmc.ncbi.nlm.nih.gov
Silver nanoparticles (AgNPs), embedded into a specific polysaccharide (EPS), were
biogenerated by Klebsiella oxytoca DSM 29614 under aerobic (AgNPs-EPSaer) and …

Cisplatin induces protective autophagy through activation of BECN1 in human bladder cancer cells

JF Lin, YC Lin, TF Tsai, HE Chen, KY Chou… - Drug design …, 2017 - Taylor & Francis
Purpose Cisplatin-based chemotherapy is the first line treatment for several cancers
including bladder cancer (BC). Autophagy induction has been implied to contribute to …

Copper (II) and/or arsenite-induced oxidative stress cascades apoptosis and autophagy in the skeletal muscles of chicken

Y Wang, H Zhao, Y Shao, J Liu, J Li, L Luo, M Xing - Chemosphere, 2018 - Elsevier
Arsenic (As) is a ubiquitous environmental toxin and robust inducer of oxidative stress (OxS).
Copper (Cu) is an essential microelement, which participates in OxS as a cofactor for certain …

MMP9 inhibition increases autophagic flux in chronic heart failure

SS Nandi, K Katsurada, NM Sharma… - American Journal …, 2020 - journals.physiology.org
Increased matrix metalloprotease 9 (MMP9) after myocardial infarction (MI) exacerbates
ischemia-induced chronic heart failure (CHF). Autophagy is cardioprotective during CHF; …

Autophagy and post-ischemic conditioning in retinal ischemia

B Mathew, M Chennakesavalu, M Sharma, LA Torres… - Autophagy, 2021 - Taylor & Francis
Retinal ischemia is a major cause of vision loss and a common underlying mechanism
associated with diseases, such as diabetic retinopathy and central retinal artery occlusion …

Resveratrol overcomes gefitinib resistance by increasing the intracellular gefitinib concentration and triggering apoptosis, autophagy and senescence in PC9/G …

Y Zhu, W He, X Gao, B Li, C Mei, R Xu, H Chen - Scientific reports, 2015 - nature.com
Gefitinib (Gef) provides clinical benefits to non-small cell lung cancer (NSCLC) patients with
activating EGFR mutations. However, acquired resistance (AR) is a major obstacle to …

Monitoring Autophagy with Atg4B Protease‐Activated Aggregation‐Induced Emission Probe

Y Lyu, X Chen, Q Wang, Q Li, Q Wang… - Advanced Functional …, 2022 - Wiley Online Library
Autophagy is crucial in the physical development and pathogenesis of disease. Monitoring
autophagy is still limited by no real‐time and poor specificity. Herein, the authors report …