Cancer is the leading cause of death worldwide. The complex and disorganized tumor
microenvironment makes it very difficult to treat this disease. The most common in vitro drug …

From microscaled capillaries to millimeter‐sized vessels, human vasculature spans multiple
scales and cell types. The convergence of bioengineering, materials science, and stem cell …

Angiogenic sprouting, the growth of new blood vessels from pre-existing vessels, is
orchestrated by cues from within the cellular microenvironment, such as biochemical …

Vascularization, the formation of new blood vessels, is an essential biological process. As
the vasculature is involved in various fundamental physiological phenomena and closely …

The microvasculature plays a critical role in human physiology and is closely associated to
various human diseases. By combining advanced microfluidic-based techniques, the …

Neovascularization, the formation of new blood vessels, has received much research
attention due to its implications for physiological processes and diseases. Most studies …

Abstract Treatment of critical-size bone defects is a major medical challenge since neither
the bone tissue can regenerate nor current regenerative approaches are effective. Emerging …

Collagen hydrogels are widely used for in-vitro experiments and tissue engineering
applications. Their use has been extended due to their biocompatibility with cells and their …

Cancer cells have the ability to migrate from the primary (original) site to other places in the
body. The extracellular matrix affects cancer cell migratory capacity and has been correlated …

Tissue engineered grafts show great potential as regenerative implants for diseased or
injured tissues within the human body. However, these grafts suffer from poor nutrient …