Cellular and molecular evidence of multiple sclerosis diagnosis and treatment challenges

Z Khan, GD Gupta, S Mehan - Journal of clinical medicine, 2023 - mdpi.com
Multiple sclerosis (MS) is a chronic autoimmune disease that impacts the central nervous
system and can result in disability. Although the prevalence of MS has increased in India …

Mycobacterium paratuberculosis zoonosis is a One Health emergency

CT Dow, BL Alvarez - Ecohealth, 2022 - Springer
A singular pathogen has been killing animals, contaminating food and causing an array of
human diseases. Mycobacterium avium subspecies paratuberculosis (MAP) is the cause of …

Genome-wide association studies for the identification of cattle susceptible and resilient to paratuberculosis

M Alonso-Hearn, G Badia-Bringué… - Frontiers in Veterinary …, 2022 - frontiersin.org
Mycobacterium avium subsp. paratuberculosis (MAP) causes Johne's disease or
paratuberculosis (PTB), with important animal health and economic implications. There are …

Identification of loci associated with pathological outcomes in Holstein cattle infected with Mycobacterium avium subsp. paratuberculosis using whole-genome …

M Canive, G Badia-Bringué, P Vázquez… - Scientific reports, 2021 - nature.com
Bovine paratuberculosis (PTB), caused by Mycobacterium avium subsp. paratuberculosis
(MAP), is a chronic granulomatous enteritis that affects cattle worldwide. According to their …

A genome-wide association study for tolerance to paratuberculosis identifies candidate genes involved in DNA packaging, DNA damage repair, innate immunity, and …

M Canive, G Badia-Bringué, P Vázquez… - Frontiers in …, 2022 - frontiersin.org
Although the genetic susceptibility to diseases has been extensively studied, the genetic loci
and the primary molecular and cellular mechanisms that control disease tolerance are still …

Potential of PINK1 and PARKIN proteins as biomarkers for active multiple sclerosis: a Japanese cohort study

D Cossu, K Yokoyama, LA Sechi, N Hattori - Frontiers in Immunology, 2021 - frontiersin.org
Background Mitochondrial dysfunction has been suggested to play an important role in all
stages of multiple sclerosis (MS). Objective To determine the expression of two mitophagy …

Epstein–Barr Virus and Human Endogenous Retrovirus in Japanese Patients with Autoimmune Demyelinating Disorders

D Cossu, Y Tomizawa, LA Sechi, N Hattori - International Journal of …, 2023 - mdpi.com
Multiple sclerosis (MS), neuromyelitis optica spectrum disorder (NMOSD), and myelin
oligodendrocytes glycoprotein-antibody disease (MOGAD) are distinct autoimmune …

Proteomic Serum Profiling of Holstein Friesian Cows with Different Pathological Forms of Bovine Paratuberculosis Reveals Changes in the Acute-Phase Response …

AI Navarro León, M Muñoz, N Iglesias… - Journal of Proteome …, 2023 - ACS Publications
The lack of sensitive diagnostic methods to detect Mycobacterium avium subsp.
paratuberculosis (Map) subclinical infections has hindered the control of paratuberculosis …

Detection of latent forms of Mycobacterium avium subsp. paratuberculosis infection using host biomarker-based ELISAs greatly improves paratuberculosis diagnostic …

C Blanco Vázquez, M Alonso-Hearn, RA Juste… - PLoS …, 2020 - journals.plos.org
Bovine paratuberculosis (PTB) is a chronic granulomatous enteritis, caused by
Mycobacterium avium subsp. paratuberculosis (MAP), responsible for important economic …

PtpA and PknG Proteins Secreted by Mycobacterium avium subsp. paratuberculosis are Recognized by Sera from Patients with Rheumatoid Arthritis: A Case …

M Bo, GL Erre, H Bach, YN Slavin… - Journal of …, 2019 - Taylor & Francis
Purpose Rheumatoid arthritis (RA) can result from complex interactions between the
affected person's genetic background and environment. Viral and bacterial infections may …