Pathogenetic mechanisms of deep infiltrating endometriosis

C Tosti, S Pinzauti, P Santulli… - Reproductive …, 2015 - journals.sagepub.com
Endometriosis is a benign gynecologic disease, affecting women of reproductive age
associated with chronic pelvic pain, dysmenorrhea, dyspareunia and infertility. Ovarian …

Endometriosis: the role of neuroangiogenesis

A Asante, RN Taylor - Annual review of physiology, 2011 - annualreviews.org
Endometriosis is a common cause of pelvic pain and infertility, affecting∼ 10% of
reproductive-age women. Annual costs for medical and surgical care in the United States …

Progesterone receptor ligands for the treatment of endometriosis: the mechanisms behind therapeutic success and failure

FM Reis, LM Coutinho, S Vannuccini… - Human …, 2020 - academic.oup.com
BACKGROUND Despite intense research, it remains intriguing why hormonal therapies in
general and progestins in particular sometimes fail in endometriosis. OBJECTIVE AND …

Mechanistic and therapeutic implications of angiogenesis in endometriosis

RN Taylor, J Yu, PB Torres, AC Schickedanz… - Reproductive …, 2009 - Springer
Like tumor metastases, endometriotic implants require neovascularization to proliferate and
invade into ectopic sites within the host. Endometrial tissue, with its robust stem cell …

Angiogenesis and endometriosis

ALL Rocha, FM Reis, RN Taylor - Obstetrics and gynecology …, 2013 - Wiley Online Library
A comprehensive review was performed to survey the role of angiogenesis in the
pathogenesis of endometriosis. This is a multifactorial disease in which the development …

Basic mechanisms of vascularization in endometriosis and their clinical implications

MW Laschke, MD Menger - Human reproduction update, 2018 - academic.oup.com
BACKGROUND Vascularization is a major hallmark in the pathogenesis of endometriosis.
An increasing number of studies suggests that multiple mechanisms contribute to the …

The role of the lymphatic system in endometriosis: a comprehensive review of the literature

LF Jerman, AJ Hey-Cunningham - Biology of reproduction, 2015 - academic.oup.com
Endometriosis is a benign gynecological disorder characterized by the presence of tissue
resembling the endometrium in locations outside the uterus. The pathogenesis of …

Targeted nanoparticles with high heating efficiency for the treatment of endometriosis with systemically delivered magnetic hyperthermia

Y Park, AA Demessie, A Luo, OR Taratula, AS Moses… - Small, 2022 - Wiley Online Library
Endometriosis is a devastating disease in which endometrial‐like tissue forms lesions
outside the uterus. It causes infertility and severe pelvic pain in≈ 176 million women …

[HTML][HTML] Management challenges of deep infiltrating endometriosis

MN D'Alterio, G D'Ancona, M Raslan… - … journal of fertility & …, 2021 - ncbi.nlm.nih.gov
Deep infiltrating endometriosis (DIE) is the most aggressive of the three phenotypes that
constitute endometriosis. It can affect the whole pelvis, subverting the anatomy and …

Polyphenols as a diet therapy concept for endometriosis—current opinion and future perspectives

A Gołąbek, K Kowalska, A Olejnik - Nutrients, 2021 - mdpi.com
Endometriosis represents an often painful, estrogen-dependent gynecological disorder,
defined by the existence of endometrial glands and stroma exterior to the uterine cavity. The …