Humans require a plethora of higher cognitive skills to perform executive functions, such as
reasoning, planning, language and social interactions, which are regulated predominantly …

Elucidating the prefrontal cortical microcircuit has been challenging, given its role in multiple
complex behaviors, including working memory, cognitive flexibility, attention, social …

Page 1 Atualizado de acordo com O DSM-5 e a CID-11 Paulo Dalgalarrondo PSICO patologia
e Semiologia dOs TranstOrnOs Mentais Page 2 Aviso Todo esforço foi feito para garantir a …

The prefrontal cortex plays an important role in shaping cognition and behavior. Many
studies have shown that medial prefrontal cortex (mPFC) plays a key role in seeking …

Rationale There is a growing body of evidence demonstrating the therapeutic potential of
ayahuasca for treating depression and anxiety. However, the mechanisms of action involved …

Although the medial prefrontal cortex (mPFC) is classically defined by its reciprocal
connections with the mediodorsal thalamic nucleus (MD), the nature of information transfer …

Abstract Fetal Alcohol Spectrum Disorders (FASD) are characterized by deficits in working
memory, response inhibition, and behavioral flexibility. However, the combination and …

Background Women are twice as likely as men to experience stress-related psychiatric
disorders. The biological basis of these sex differences is poorly understood. Orexins are …

The layout of areas in the cerebral cortex of different primates is quite similar, despite
significant variations in brain size. However, it is clear that larger brains are not simply …

The Akt family of kinases exerts many of its cellular effects via the activation of the
mammalian target of rapamycin (mTOR) kinase through a series of intermediary proteins …