The main function of the lung is to perform gas exchange while maintaining lung
homeostasis despite environmental pathogenic and non-pathogenic elements contained in …

Pulmonary fibrosis (PF) is a chronic and relentlessly progressive interstitial lung disease in
which the accumulation of fibroblasts and extracellular matrix (ECM) induces the destruction …

Adult lung resident stem/progenitor cells, including P63+ progenitor cells, have
demonstrated the capacity for regeneration of lung epithelium in preclinical models. Here …

COVID-19 survivors often suffer from post-acute sequelae of SARS-CoV-2 infection (PASC).
Current evidence suggests dysregulated alveolar regeneration as a possible explanation for …

Extensive tracheal injury or disease can be life-threatening but there is currently no standard
of care. Regenerative medicine offers a potential solution to long-segment tracheal defects …

Bronchopulmonary dysplasia (BPD) is a chronic lung disease commonly seen in preterm
infants, and is triggered by infection, mechanical ventilation, and oxygen toxicity. Among …

Cancer stem cells (CSCs) play an important role in cancer development. Based on
advancements in CSC research, we propose a monophyletic model of cancer. This model is …

In chronic obstructive pulmonary disease (COPD), the progressive loss of lung tissue is
widely considered irreversible. Thus, various treatment and rehabilitation schemes …

Chronic lung diseases including asthma, chronic obstructive pulmonary disease (COPD)
and lung fibrosis represent a major burden on healthcare systems with limited effective …

We applaud the proposal of Celli and colleagues (1) to provide an updated definition of
chronic obstructive pulmonary disease (COPD), driven by the slow progress of therapeutic …