Single molecules can now be visualised with unprecedented precision. As the resolution of
single-molecule experiments improves, so too does the breadth, quantity and quality of …

A challenge in developing proteolysis targeting chimeras (PROTACs) is the establishment of
a universal platform applicable in multiple scenarios for precise degradation of proteins of …

Conspectus DNA nanotechnology relies on the molecular recognition properties of DNA to
produce complex architectures through self-assembly. The resulting DNA nanostructures …

The development of a synthetic code that enables a sequence programmable feature like
DNA represents a key aspect toward intelligent molecular systems. We developed herein …

DNA nanotechnology has revolutionized the ability to position matter at the nanoscale, but
the preparation of DNA‐based architectures remains laborious. To facilitate the formation of …

Nucleated protein self-assembly of an azido modified spider silk protein was employed in
the preparation of nanofibrillar networks with hydrogel-like properties immobilized on …

The toehold-mediated strand displacement reaction (SDR) is a powerful enzyme-free tool for
molecular manipulation, DNA computing, signal amplification, etc. However, precise …

The targeted and direct intracellular delivery of proteins plays critical roles in biological
research and disease treatments, yet remains highly challenging. Current solutions to such …

DNA nanotechnology and advances in the DNA origami technique have enabled facile
design and synthesis of complex and functional nanostructures. Molecular devices are …

Nanotubes built from DNA hold promise for several biological and materials applications,
due to their high aspect ratio and encapsulation potential. A particularly appealing goal is to …