What startles tell us about control of posture and gait

J Nonnekes, MG Carpenter, JT Inglis, J Duysens… - Neuroscience & …, 2015 - Elsevier
Recently, there has been an increase in studies evaluating startle reflexes and StartReact,
many in tasks involving postural control and gait. These studies have provided important …

Treatment of spasticity

J Marsden, V Stevenson, L Jarrett - Handbook of Clinical Neurology, 2023 - Elsevier
Spasticity is characterized by an enhanced size and reduced threshold for activation of
stretch reflexes and is associated with “positive signs” such as clonus and spasms, as well …

Subcortical structures in humans can be facilitated by transcranial direct current stimulation

J Nonnekes, A Arrogi, MAM Munneke… - PloS one, 2014 - journals.plos.org
Transcranial direct current stimulation (tDCS) is a noninvasive brain stimulation technique
that alters cortical excitability. Interestingly, in recent animal studies facilitatory effects of …

Robotic gait training improves motor skills and quality of life in hereditary spastic paraplegia

F Bertolucci, S Di Martino, D Orsucci… - …, 2015 - content.iospress.com
Background: Gait impairment, balance problems and falls have a negative impact on
independence in ADL and quality of life of patients affected by Hereditary Spastic …

StartReact effects support different pathophysiological mechanisms underlying freezing of gait and postural instability in Parkinson's disease

J Nonnekes, D de Kam, LBO Nijhuis, K van Geel… - PLoS …, 2015 - journals.plos.org
Introduction The pathophysiology underlying postural instability in Parkinson's disease is
poorly understood. The frequent co-existence with freezing of gait raises the possibility of …

Experienced complaints, activity limitations and loss of motor capacities in patients with pure hereditary spastic paraplegia: a web-based survey in the Netherlands

BJH van Lith, HCJW Kerstens… - Orphanet journal of rare …, 2020 - Springer
Background Hereditary spastic paraplegia (HSP) is a group of inherited disorders
characterized by progressive spastic paresis of the lower limbs. Treatment is often focused …

Non-pharmacological treatment of hereditary spastic paraplegia: a systematic review

S Maccora, A Torrente, V Di Stefano, A Lupica… - Neurological …, 2024 - Springer
Objectives The aim is to investigate the use of non-pharmacological treatments in HSP,
including magnetic field therapy, acupuncture, laser therapy, surgery, electric stimulation …

Offline effects of transcranial direct current stimulation on reaction times of lower extremity movements in people after stroke: a pilot cross-over study

MJM Coppens, WHA Staring, J Nonnekes… - … of neuroengineering and …, 2019 - Springer
Background Transcranial direct current stimulation (tDCS) is a non-invasive brain
stimulation technique that has shown promise for rehabilitation after stroke. Ipsilesional …

Gait phenotypes in paediatric hereditary spastic paraplegia revealed by dynamic time warping analysis and random forests

I Pulido-Valdeolivas, D Gómez-Andrés… - PLoS …, 2018 - journals.plos.org
The Hereditary Spastic Paraplegias (HSP) are a group of heterogeneous disorders with a
wide spectrum of underlying neural pathology, and hence HSP patients express a variety of …

A startling acoustic stimulus facilitates voluntary lower extremity movements and automatic postural responses in people with chronic stroke

MJM Coppens, JMB Roelofs, NAJ Donkers… - Journal of …, 2018 - Springer
A startling acoustic stimulus (SAS) involuntary releases prepared movements at accelerated
latencies, known as the StartReact effect. Previous work has demonstrated intact StartReact …