Foot-and-mouth disease

MJ Grubman, B Baxt - Clinical microbiology reviews, 2004 - Am Soc Microbiol
Foot-and-mouth disease (FMD) is a highly contagious disease of cloven-hoofed animals.
The disease was initially described in the 16th century and was the first animal pathogen …

Development of vaccines toward the global control and eradication of foot-and-mouth disease

LL Rodriguez, CG Gay - Expert review of vaccines, 2011 - Taylor & Francis
Foot-and-mouth disease (FMD) is one of the most economically and socially devastating
diseases affecting animal agriculture throughout the world. Although mortality is usually low …

[HTML][HTML] Rapid protection of cattle from direct challenge with foot-and-mouth disease virus (FMDV) by a single inoculation with an adenovirus-vectored FMDV subunit …

JM Pacheco, MCS Brum, MP Moraes, WT Golde… - Virology, 2005 - Elsevier
We have previously demonstrated that swine vaccinated with one dose of a replication-
defective human adenovirus type 5 (Ad5) vector containing the capsid and 3C proteinase …

The prevalence of foot-and-mouth disease in Asia

M Aslam, KA Alkheraije - Frontiers in Veterinary Science, 2023 - frontiersin.org
Foot-and-mouth disease (FMD) is listed among the highly contagious diseases in animals
and is endemic throughout the Asian continent. The disease is caused by the Foot-and …

[HTML][HTML] Antiviral activity of bovine type III interferon against foot-and-mouth disease virus

F Díaz-San Segundo, M Weiss, E Perez-Martín… - Virology, 2011 - Elsevier
Foot-and-mouth disease (FMD) is one of the most serious threats to the livestock industry.
Despite the availability of a vaccine, recent outbreaks in disease-free countries have …

Bovine type III interferon significantly delays and reduces the severity of foot-and-mouth disease in cattle

E Perez-Martin, M Weiss, F Diaz-San Segundo… - Journal of …, 2012 - Am Soc Microbiol
Interferons (IFNs) are the first line of defense against viral infections. Although type I and II
IFNs have proven effective to inhibit foot-and-mouth disease virus (FMDV) replication in …

Recombinant swine beta interferon protects swine alveolar macrophages and MARC-145 cells from infection with Porcine reproductive and respiratory syndrome virus

C Overend, R Mitchell, D He… - Journal of general …, 2007 - microbiologyresearch.org
Swine beta interferon (swIFN-β) produced in HEK 293 cells infected with a recombinant,
replication-defective human adenovirus 5 (Ad5) encoding the swIFN-β gene was tested for …

The different tactics of foot-and-mouth disease virus to evade innate immunity

GN Medina, FDS Segundo, C Stenfeldt, J Arzt… - Frontiers in …, 2018 - frontiersin.org
Like all pathogens, foot-and-mouth disease virus (FMDV) is recognized by the immune
system inducing a heightened immune response mainly mediated by type I and type III IFNs …

Porcine type I interferon rapidly protects swine against challenge with multiple serotypes of foot-and-mouth disease virus

CCA Dias, MP Moraes, FDS Segundo… - Journal of interferon & …, 2011 - liebertpub.com
Foot-and-mouth disease virus (FMDV) causes a highly contagious disease of cloven-hoofed
animals. Current inactivated vaccines require approximately 7 days to induce protection, but …

Potential of antiviral therapy and prophylaxis for controlling RNA viral infections of livestock

N Goris, F Vandenbussche, K De Clercq - Antiviral research, 2008 - Elsevier
With intensification of trade, livestock are increasingly exposed to severe animal diseases
caused by a range of RNA viruses. Recent prime examples include outbreaks of foot-and …