Chemical tools have accelerated progress in glycoscience, reducing experimental barriers
to studying protein glycosylation, the most widespread and complex form of posttranslational …

Cell death is a fundamental physiological process that occurs in all organisms and is crucial
to each organism's evolution, ability to maintain a stable internal environment, and the …

Background—The clinical use of doxorubicin is limited by cardiotoxicity. Histopathological
changes include interstitial myocardial fibrosis and the appearance of vacuolated …

Cell surface proteins are major targets of biomedical research due to their utility as cellular
markers and their extracellular accessibility for pharmacological intervention. However …

Abstract PDX1+/NKX6-1+ pancreatic progenitors (PPs) give rise to endocrine cells both in
vitro and in vivo. This cell population can be successfully differentiated from human …

Protein glycosylation is ubiquitous in biological systems and plays essential roles in many
cellular events. Global and site‐specific analysis of glycoproteins in complex biological …

Human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) are the most promising
source of cardiomyocytes (CMs) for experimental and clinical applications, but their use is …

There is an urgent need to develop approaches for repairing the damaged heart,
discovering new therapeutic drugs that do not have toxic effects on the heart, and improving …

Background Targeting glucose metabolism is a promising way to interfere with tumor cell
proliferation and survival. However, controversy exists about the specificity of some glucose …

Pigment Epithelium Derived Factor (PEDF) is a secreted factor that has broad biological
activities. It was first identified as a neurotrophic factor and later as the most potent natural …