In mammals, hundreds of proteins use iron in a multitude of cellular functions, including vital
processes such as mitochondrial respiration, gene regulation and DNA synthesis or repair …

The maintenance of iron homeostasis is essential for proper cardiac function. A growing
body of evidence suggests that iron imbalance is the common denominator in many …

Ferroptosis is an iron-dependent form of non-apoptotic cell death characterized by
excessive lipid peroxidation and associated with a plethora of pathological conditions in the …

Cell death can be executed through different subroutines. Since the description of
ferroptosis as an iron-dependent form of non-apoptotic cell death in 2012, there has been …

An abundant metal in the human body, iron is essential for key biological pathways
including oxygen transport, DNA metabolism, and mitochondrial function. Most iron is bound …

Ferroptosis, an intricately regulated form of cell death characterized by uncontrolled lipid
peroxidation, has garnered substantial interest since this term was first coined in 2012 …

Ferroptosis is an iron-dependent, non-apoptotic form of regulated cell death caused by lipid
peroxidation, which is controlled by integrated oxidation and antioxidant systems. The iron …

Ferroptosis is a mechanism of regulated necrotic cell death characterized by iron-
dependent, lipid peroxidation-driven membrane destruction that can be inhibited by …

Ferroptosis is a form of regulated cell death that is characterized by iron-dependent
oxidative damage and subsequent plasma membrane ruptures and the release of damage …

The induction and consequences of regulated cell death (RCD) are accompanied by
changes in gene and protein expression, biochemical pathways, as well as cell morphology …