Genetics of human hydrocephalus

J Zhang, MA Williams, D Rigamonti - Journal of neurology, 2006 - Springer
Human hydrocephalus is a common medical condition that is characterized by abnormalities
in the flow or resorption of cerebrospinal fluid (CSF), resulting in ventricular dilatation …

Familial aggregation of idiopathic normal pressure hydrocephalus: novel familial case and a family study of the NPH triad in an iNPH patient cohort

A McGirr, MD Cusimano - Journal of the neurological sciences, 2012 - Elsevier
OBJECTIVE: Idiopathic normal pressure hydrocephalus (iNPH) is considered sporadic, yet
familial cases involving single pedigrees are being increasingly recognized. As current …

Normal-pressure hydrocephalus: is there a genetic predisposition?

MD Cusimano, D Rewilak, DT Stuss… - Canadian journal of …, 2011 - cambridge.org
Background: Normal-pressure hydrocephalus (NPH) is characterized by gait disturbance,
cognitive impairment, with or without urinary incontinence, enlarged ventricles with or …

Risk factors of congenital hydrocephalus: a 10 year retrospective study

M Van Landingham, TV Nguyen, A Roberts… - Journal of Neurology …, 2009 - jnnp.bmj.com
Objective: To evaluate and identify the risk factors associated with the pathogenesis of
congenital hydrocephalus in a large specific population. Methods: An International …

[HTML][HTML] Disruption of the mouse Jhy gene causes abnormal ciliary microtubule patterning and juvenile hydrocephalus

OK Appelbe, B Bollman, A Attarwala, LA Triebes… - Developmental …, 2013 - Elsevier
Congenital hydrocephalus, the accumulation of excess cerebrospinal fluid (CSF) in the
ventricles of the brain, affects one of every 1000 children born today, making it one of the …

Longitudinal evaluation of an N-ethyl-N-nitrosourea-created murine model with normal pressure hydrocephalus

MJ Lee, CP Chang, YH Lee, YC Wu, HW Tseng… - PloS one, 2009 - journals.plos.org
Background Normal-pressure hydrocephalus (NPH) is a neurodegenerative disorder that
usually occurs late in adult life. Clinically, the cardinal features include gait disturbances …

Diabetes is associated with familial idiopathic normal pressure hydrocephalus: a case–control comparison with family members

J Räsänen, J Huovinen, VE Korhonen… - Fluids and Barriers of …, 2020 - Springer
Background The pathophysiological basis of idiopathic normal pressure hydrocephalus
(iNPH) is still unclear. Previous studies have shown a familial aggregation and a potential …

Hydrocephalus and genetic disorders

A Dalla Corte, F de Oliveira Poswar… - Cerebrospinal Fluid and …, 2023 - Elsevier
A growing body of evidence indicates that genetic factors play a major role in the
pathogenesis of hydrocephalus. An understanding of the genetic components and …

[PDF][PDF] Identical twins with idiopathic normal pressure hydrocephalus

A Eleftheriou, F Lundin - J Neurol Disord, 2017 - researchgate.net
Background: The pathogenesis of iNPH is inadequately known. Small vessel disease seems
to play an important role but the link to a disturbed CSF dynamic is not described. The …

[PDF][PDF] Genetics of Hydrocephalus (HC)

I Naureen, A Saleem, M Ghafoor, FM Ali, N Murad… - 2022 - easpublisher.com
Genetic hydrocephalus is a neurological condition in which the cerebrospinal fluid (CSF)
flows with subsequent and it results in enlargement of the cerebral ventricular cavities. The …