An update on molecular diagnostics for COVID-19

KU Islam, J Iqbal - Frontiers in cellular and infection microbiology, 2020 - frontiersin.org
A novel strain of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) disease
(COVID-19) has been recently identified as an infectious disease affecting the respiratory …

Versatile detection with CRISPR/Cas system from applications to challenges

H Wu, X Chen, M Zhang, X Wang, Y Chen… - TrAC Trends in …, 2021 - Elsevier
CRISPR/Cas system is now playing an important role in biosensing applications, especially
when the trans cleavage activity of several Cas effectors is discovered. Recently …

Molecular diagnostic assays for COVID-19: an overview

P Habibzadeh, M Mofatteh, M Silawi… - Critical reviews in …, 2021 - Taylor & Francis
Abstract The coronavirus disease 2019 (COVID-19) pandemic has highlighted the cardinal
importance of rapid and accurate diagnostic assays. Since the early days of the outbreak …

A saliva-based RNA extraction-free workflow integrated with Cas13a for SARS-CoV-2 detection

I Azmi, MI Faizan, R Kumar, S Raj Yadav… - Frontiers in Cellular …, 2021 - frontiersin.org
A major bottleneck in scaling-up COVID-19 testing is the need for sophisticated instruments
and well-trained healthcare professionals, which are already overwhelmed due to the …

The relevant information about the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) using the five-question approach (when, where, what, why, and …

FA AlMalki, S Albukhaty, AA Alyamani… - … Science and Pollution …, 2023 - Springer
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is regarded as a threat
because it spreads quickly across the world without requiring a passport or establishing an …

[HTML][HTML] Point-of-need detection of pathogen-specific nucleic acid targets using magnetic particle spectroscopy

EL Rösch, J Zhong, A Lak, Z Liu, M Etzkorn… - Biosensors and …, 2021 - Elsevier
The ongoing COVID-19 pandemic stresses the need for widely available diagnostic tests for
the presence of SARS-CoV-2 in individuals. Due to the limited availability of vaccines …

HEPN RNases–an emerging class of functionally distinct RNA processing and degradation enzymes

MC Pillon, J Gordon, MN Frazier… - Critical reviews in …, 2021 - Taylor & Francis
Abstract HEPN (Higher Eukaryotes and Prokaryotes Nucleotide-binding) RNases are an
emerging class of functionally diverse RNA processing and degradation enzymes. Members …

Epidemic spreading and digital contact tracing: Effects of heterogeneous mixing and quarantine failures

AK Rizi, A Faqeeh, A Badie-Modiri, M Kivelä - Physical Review E, 2022 - APS
Contact tracing via digital tracking applications installed on mobile phones is an important
tool for controlling epidemic spreading. Its effectivity can be quantified by modifying the …

[HTML][HTML] Rapid, point-of-care molecular diagnostics with Cas13

S Agrawal, A Fanton, SS Chandrasekaran, B Charrez… - MedRxiv, 2021 - ncbi.nlm.nih.gov
Rapid nucleic acid testing is a critical component of a robust infrastructure for increased
disease surveillance. Here, we report a microfluidic platform for point-of-care, CRISPR …

Portable tools for COVID-19 point-of-care detection: A review

EF Saki, SA Setiawan, DHB Wicaksono - IEEE Sensors Journal, 2021 - ieeexplore.ieee.org
Recently, several methods for SARS-CoV-2 detection have been developed to obtain rapid,
portable, cheap, and easy-to-use diagnostic tools. This review paper summarizes and …