Hyperlipidemia is a major risk factor for cardiovascular morbidity and mortality. Statins are
the first-choice therapy for dyslipidemias and are considered the cornerstone of …

Statins are a cornerstone in the pharmacological prevention of cardiovascular disease.
Although generally well tolerated, a small subset of patients experience statin-related …

Background Vitamin D status has been implicated in COVID-19 disease. The objective of the
COVID-VIT-D trial was to investigate if an oral bolus of cholecalciferol (100,000 IU) …

Statins are effective drugs to reduce cardiovascular events secondary to dyslipidemia;
however, they cause frequent undesirable side effects. The incidence of statin-induced …

Since the first approval of lovastatin in 1987, hydroxy-methyl-glutaryl CoA (HMG CoA)
reductase inhibitors, or statins, have been effective and widely popular cholesterol-lowering …

In recent years, clinical trials increasingly have given large doses of vitamin D supplements
to investigate possible health benefits beyond bone at high 25-hydroxyvitamin D levels …

Interactions between drugs and micronutrients have received only little or no attention in the
medical and pharmaceutical world in the past. Since more and more pharmaceutics are …

Background Low serum 25-hydroxy-vitamin D [25 (OH) D] levels are prevalent worldwide.
Although the benefits of vitamin D supplementation have focused on skeletal disorders (eg …

Background The study objectives were to ascertain the efficacy of vitamin D
supplementation in rapidly increasing serum vitamin D and of implementation of a hybrid …

Background: Older adults are prone to vitamin D3 (VD3) deficiency, which may impair their
health. A high dose of VD3 (HDVD3= 100,000 IU) could improve their 25-hydroxyvitamin D3 …