Cycling glial precursors—" NG2-glia"—are abundant in the developing and mature central
nervous system (CNS). During development, they generate oligodendrocytes. In culture …

Several years ago, the discovery of a highly tumorigenic subpopulation of stem-like cells
embedded within fresh surgical isolates of malignant gliomas lent support to a new …

Glial cells have been identified as key signaling components in the brain; however, methods
to investigate their structure and function in vivo have been lacking. Here, we describe a …

The precursor function of the ubiquitous glial cell type in the developing central nervous
system (CNS), the radial glia, is largely unknown. Using Cre/loxP in vivo fate mapping …

Endothelial differentiation gene (Edg) proteins are G-protein-coupled receptors activated by
lysophospholipid mediators: sphingosine-1-phosphate (S1P) or lysophosphatidic acid. We …

Recent data have suggested the existence of direct signaling pathways between glial cells
and neurons. Here we report the coexistence of distinct types of cells expressing astrocyte …

The role of glia in modulating neuronal network activity is an important question.
Oligodendrocyte precursor cells (OPC) characteristically express the transmembrane …

The NG2 proteoglycan is a type 1-transmembrane protein expressed by a range of cell types
within and outside the mammalian nervous system. NG2-expressing (NG2) cells are found …

Rouget, in 1873, was the first to describe a population of cells surrounding capillaries, which
he regarded as contractile elements. Fifty years later, Zimmermann termed these cells …

NG2 (nerve/glia antigen‐2) is a type I transmembrane glycoprotein and also known as
chondroitin sulfate proteoglycan 4. In the parenchyma of the central nervous system, NG2 …