Natural products from fungi represent an important source of biologically active metabolites
notably for therapeutic agent development. Genome sequencing revealed that the number …

Aspergillus niger, one of the most common and important fungal species, is ubiquitous in
various environments. A. niger isolates possess a large number of cryptic biosynthetic gene …

Secondary metabolites (SMs) produced by filamentous fungi possess diverse bioactivities
that make them excellent drug candidates. Whole genome sequencing has revealed that …

Reactive functional groups, such as N-nitrosamines, impart unique bioactivities to the
natural products in which they are found. Recent work has illuminated enzymatic N …

Fungal polyketide–nonribosomal peptide (PK–NRP) hybrid macrolactones are a growing
family of natural products with biomedical and agricultural activities. One of the most …

Covering: 1999 up to 2021 Fungal polyketides encompass a range of structurally diverse
molecules with a wide variety of biological activities. The giant multifunctional enzymes that …

Berberine bridge enzyme-like oxidases are often involved in natural product biosynthesis
and are seen as essential enzymes for the generation of intricate pharmacophores. These …

Fungal polyketide synthase (PKS)–nonribosomal peptide synthetase (NRPS) hybrids are
key enzymes for synthesizing structurally diverse hybrid natural products (NPs) with …

Covering: up to the end of 2020 Natural products bearing tetramic acid units as part of
complex molecular architectures exhibit a broad range of potent biological activities. These …

Aspergillus niger is a phytopathogenic fungus responsible for the plant disease called “black
mold”, and it is considered the most versatile microorganism for producing acids, proteins …