Cancer is characterized by the uncontrolled division of cells, resulting in the formation of
tumors. The tumor microenvironment (TME) consists of a variety of cell types present within a …

The tumor microenvironment plays a crucial role in cancer development and treatment.
Traditional 2D cell cultures fail to fully replicate the complete tumor microenvironment, while …

Existing organoid models fall short of fully capturing the complexity of cancer because they
lack sufficient multicellular diversity, tissue-level organization, biological durability and …

In cancer microenvironment, aberrant glycosylation events of ECM proteins and cell surface
receptors occur. We developed a protocol to generate 3D bioprinted models of colorectal …

Simple Summary Although many new cancer drugs look like they are working in the
laboratory, they fail when tested on real people. This is often because the cancer cell models …

Methods accurately predicting the responses of colorectal cancer (CRC) and colorectal
cancer liver metastasis (CRLM) to personalized chemotherapy remain limited due to tumor …

Abstract Three-dimensional (3D) bioprinting is a novel technology that enables the creation
of 3D structures with bioinks, the biomaterials containing living cells. 3D bioprinted …

Hepato-pancreato-biliary (HPB) cancer is a serious category of cancer including tumors
originating in the liver, pancreas, gallbladder and biliary ducts. It is limited by two …

Malignant tumor tissues exhibit inter-and intratumoral heterogeneities, aberrant
development, dynamic stromal composition, diverse tissue phenotypes, and cell populations …

The ability of three-dimensional (3D) bioprinting to fabricate biomimetic organ and disease
models has been recognised to be promising for drug discovery and development as 3D …