Haemocyte‐mediated immunity in insects: Cells, processes and associated components in the fight against pathogens and parasites

I Eleftherianos, C Heryanto, T Bassal, W Zhang… - …, 2021 - Wiley Online Library
The host defence of insects includes a combination of cellular and humoral responses. The
cellular arm of the insect innate immune system includes mechanisms that are directly …

Drosophila as a Genetic Model for Hematopoiesis

U Banerjee, JR Girard, LM Goins, CM Spratford - Genetics, 2019 - academic.oup.com
In this FlyBook chapter, we present a survey of the current literature on the development of
the hematopoietic system in Drosophila. The Drosophila blood system consists entirely of …

Transdifferentiation and Proliferation in Two Distinct Hemocyte Lineages in Drosophila melanogaster Larvae after Wasp Infection

I Anderl, L Vesala, TO Ihalainen, LM Vanha-Aho… - PLoS …, 2016 - journals.plos.org
Cellular immune responses require the generation and recruitment of diverse blood cell
types that recognize and kill pathogens. In Drosophila melanogaster larvae, immune …

Macrophages and cellular immunity in Drosophila melanogaster

KS Gold, K Brückner - Seminars in Immunology, 2015 - Elsevier
The invertebrate Drosophila melanogaster has been a powerful model for understanding
blood cell development and immunity. Drosophila is a holometabolous insect, which …

An entomopathogenic fungus exploits its host humoral antibacterial immunity to minimize bacterial competition in the hemolymph

JL Wang, J Sun, YJ Song, HH Zheng, GJ Wang… - Microbiome, 2023 - Springer
Background The insect hemolymph (blood-equivalent fluid), composed of a large number of
hemocytes (blood cells) and a variety of soluble immune effectors, is hostile for pathogens …

Drosophila hematopoiesis under normal conditions and in response to immune stress

M Letourneau, F Lapraz, A Sharma, N Vanzo… - FEBS …, 2016 - Wiley Online Library
The emergence of hematopoietic progenitors and their differentiation into various highly
specialized blood cell types constitute a finely tuned process. Unveiling the genetic …

Drosophila Cellular Immunity Against Parasitoid Wasps: A Complex and Time-Dependent Process

C Kim-Jo, JL Gatti, M Poirié - Frontiers in Physiology, 2019 - frontiersin.org
Host-parasitoid interactions are among the most studied interactions between invertebrates
because of their fundamental interest–the evolution of original traits in parasitoids–and …

Reactive oxygen species-dependent Toll/NF-κB activation in the Drosophila hematopoietic niche confers resistance to wasp parasitism

I Louradour, A Sharma, I Morin-Poulard, M Letourneau… - Elife, 2017 - elifesciences.org
Hematopoietic stem/progenitor cells in the adult mammalian bone marrow ensure blood cell
renewal. Their cellular microenvironment, called 'niche', regulates hematopoiesis both under …

Cytokine Diedel and a viral homologue suppress the IMD pathway in Drosophila

O Lamiable, C Kellenberger, C Kemp… - Proceedings of the …, 2016 - National Acad Sciences
Viruses are obligatory intracellular parasites that suffer strong evolutionary pressure from the
host immune system. Rapidly evolving viral genomes can adapt to this pressure by …

Cellular and humoral immune interactions between Drosophila and its parasitoids

L Yang, LM Qiu, Q Fang, DW Stanley, GY Ye - Insect Science, 2021 - Wiley Online Library
The immune interactions occurring between parasitoids and their host insects, especially in
Drosophila–wasp models, have long been the research focus of insect immunology and …