Nutraceutical Role of Polyphenols and Triterpenes Present in the Extracts of Fruits and Leaves of Olea europaea as Antioxidants, Anti-Infectives and Anticancer …

EE Rufino-Palomares, A Pérez-Jiménez… - Molecules, 2022 - mdpi.com
There is currently a worldwide consensus and recognition of the undoubted health benefits
of the so-called Mediterranean diet, with its intake being associated with a lower risk of …

Application of cinnamic acid in the structural modification of natural products: A review

H Deng, Q Xu, HY Guo, X Huang, F Chen, L Jin… - Phytochemistry, 2023 - Elsevier
Natural products can generally exhibit a variety of biological activities, but most show
mediocre performance in preliminary activity evaluation. Natural products often require …

[HTML][HTML] Evaluation of bioactive compounds from Ficus carica L. leaf extracts via high-performance thin-layer chromatography combined with effect-directed analysis

S Agatonovic-Kustrin, S Wong, AV Dolzhenko… - … of Chromatography A, 2023 - Elsevier
This study compares different solvent systems with the use of spontaneous fermentation on
the phytochemical composition of leaf extracts from a locally grown white variety of common …

Investigation of Novel Mucorales Fungal Inhibitors: Synthesis, In‐Silico Study and Anti‐Fungal Potency of Novel Class of Coumarin‐6‐Sulfonamides‐Thiazole and …

A Sabt, MT Abdelrahman, M Abdelraof… - …, 2022 - Wiley Online Library
A series of coumarin‐6‐sulfonamides derivatives bearing a thiazole and thiadiazole scaffold
were synthesized, their chemical structures were inferred from correct spectral and …

Bioactivities and structure‐activity relationships of maslinic acid derivatives: a review

R Yan, L Liu, X Huang, ZS Quan… - Chemistry & …, 2024 - Wiley Online Library
Maslinic acid has a variety of biological activities, such as anti‐tumor, hypoglycemic, anti‐
inflammatory, and anti‐parasitic. In order to enhance the biological activity of maslinic acid …

Evaluation of Anticancer and Anti-Inflammatory Activities of Some Synthetic Rearranged Abietanes

M Ait El Had, H Zentar, B Ruiz-Muñoz, J Sainz… - International Journal of …, 2023 - mdpi.com
Synthesis of the rearranged abietane diterpenes pygmaeocins C and D, viridoquinone,
saprorthoquinone, and 1-deoxyviroxocine has been successfully achieved. The anticancer …

Semisynthesis and Evaluation of Anti-Inflammatory Activity of the Cassane-Type Diterpenoid Taepeenin F and of Some Synthetic Intermediates

H Zentar, F Jannus, P Gutierrez… - Journal of Natural …, 2022 - ACS Publications
A new strategy for the semisynthesis of the aromatic cassane-type diterpene taepeenin F (6)
is reported. The introduction of the methyl group at C-14, characteristic of the target …

[HTML][HTML] Synthesis, solubility and antitumor activity of maslinic acid derivatives

D Fuentes-Rios, A Cepero, M García-Castro… - European Journal of …, 2022 - Elsevier
Maslinic acid (MA), a pentacyclic triterpenoid obtained from olives that is characterized by its
antiproliferative activity in tumor cells, has become a promising molecule that could be …

Synthesis, Molecular Electron Density Theory Study, Molecular Docking, and Pharmacological Evaluation of New Coumarin–Sulfonamide–Nitroindazolyl–Triazole …

M Eddahmi, G La Spada, LR Domingo… - International Journal of …, 2024 - mdpi.com
Inhibitors of monoamine oxidases (MAOs) are of interest for the treatment of
neurodegenerative disorders and other human pathologies. In this frame, the present work …

Novel Coumarins Derivatives for A. baumannii Lung Infection Developed by High-Throughput Screening and Reinforcement Learning

J Li, Z Lu, L Wang, H Shi, B Chu, Y Qu, Z Ye… - Journal of Neuroimmune …, 2024 - Springer
With the increasing resistance of Acinetobacter baumannii (A. baumannii) to antibiotics,
researchers have turned their attention to the development of new antimicrobial agents …