The ideal drug delivery system has a bioavailability comparable to parenteral dosage forms
but is as convenient and easy to use for the patient as oral solid dosage forms. In recent …

The skin offers an accessible and convenient site for the administration of medications. To
this end, the field of transdermal drug delivery, aimed at developing safe and efficacious …

Biofilm infection has a high prevalence in chronic wounds and can delay wound healing.
Current treatment using debridement and antibiotic administration imposes a significant …

Transdermal drug delivery has made an important contribution to medical practice, but has
yet to fully achieve its potential as an alternative to oral delivery and hypodermic injections …

The past twenty five years have seen an explosion in the creation and discovery of new
medicinal agents. Related innovations in drug delivery systems have not only enabled the …

The protective function of human skin imposes physicochemical limitations to the type of
permeant that can traverse the barrier. For a drug to be delivered passively via the skin it …

This paper covers the main medical applications of artificial membranes. Specific attention is
given to drug delivery systems, artificial organs and tissue engineering which seem to …

The techniques of iontophoresis and electroporation can be used to enhance topical and
transdermal drug delivery. Iontophoresis applies a small low voltage (typically 10 V or less) …

The recent approval of lidocaine hydrochloride and epinephrine combined iontophoretic
patch (Lidosite® Vysteris Inc.) for localized pain treatment by FDA has invigorated the …

In vivo electroporation, first reported in 1987, makes it possible to render cell membranes
temporarily permeable to substances that otherwise would not be able to effectively enter …