[HTML][HTML] The microbiome and irritable bowel syndrome–a review on the pathophysiology, current research and future therapy

PP Chong, VK Chin, CY Looi, WF Wong… - Frontiers in …, 2019 - frontiersin.org
Irritable bowel syndrome (IBS) is a functional disorder which affects a large proportion of the
population globally. The precise etiology of IBS is still unknown, although consensus …

Increased intestinal permeability and decreased barrier function: does it really influence the risk of inflammation?

H Fukui - Inflammatory intestinal diseases, 2016 - karger.com
Background: Increased intestinal permeability due to barrier dysfunction is supposed to
cause microbial translocation which may induce low-grade inflammation in various …

[HTML][HTML] Identification of an intestinal microbiota signature associated with severity of irritable bowel syndrome

J Tap, M Derrien, H Törnblom, R Brazeilles… - Gastroenterology, 2017 - Elsevier
Background & Aims We have limited knowledge about the association between the
composition of the intestinal microbiota and clinical features of irritable bowel syndrome …

[HTML][HTML] Gut microbes promote colonic serotonin production through an effect of short-chain fatty acids on enterochromaffin cells

CS Reigstad, CE Salmonson, JF Rainey III… - The FASEB …, 2014 - pmc.ncbi.nlm.nih.gov
Gut microbiota alterations have been described in several diseases with altered
gastrointestinal (GI) motility, and awareness is increasing regarding the role of the gut …

Microbiota regulation of the mammalian gut–brain axis

A Burokas, RD Moloney, TG Dinan, JF Cryan - Advances in applied …, 2015 - Elsevier
The realization that the microbiota–gut–brain axis plays a critical role in health and disease
has emerged over the past decade. The brain–gut axis is a bidirectional communication …

Fecal microbiota transplantation as new therapeutic avenue for human diseases

M Biazzo, G Deidda - Journal of Clinical Medicine, 2022 - mdpi.com
The human body is home to a variety of micro-organisms. Most of these microbial
communities reside in the gut and are referred to as gut microbiota. Over the last decades …

A clinician's primer on the role of the microbiome in human health and disease

S Khanna, PK Tosh - Mayo clinic proceedings, 2014 - Elsevier
The importance of the commensal microbiota that colonizes the skin, gut, and mucosal
surfaces of the human body is being increasingly recognized through a rapidly expanding …

[HTML][HTML] Beneficial modulation of the gut microbiota

CJ Walsh, CM Guinane, PW O'Toole, PD Cotter - FEBS letters, 2014 - Elsevier
The human gut microbiota comprises approximately 100 trillion microbial cells and has a
significant effect on many aspects of human physiology including metabolism, nutrient …

[HTML][HTML] Differences in fecal microbiomes and metabolomes of people with vs without irritable bowel syndrome and bile acid malabsorption

IB Jeffery, A Das, E O'Herlihy, S Coughlan, K Cisek… - Gastroenterology, 2020 - Elsevier
Background & Aims Irritable bowel syndrome (IBS) is a heterogeneous disorder, but
diagnoses and determination of subtypes are made based on symptoms. We profiled the …

[HTML][HTML] Effects of a high fat diet on intestinal microbiota and gastrointestinal diseases

M Zhang, XJ Yang - World journal of gastroenterology, 2016 - ncbi.nlm.nih.gov
Along with the rapid development of society, lifestyles and diets have gradually changed.
Due to overwhelming material abundance, high fat, high sugar and high protein diets are …