There is rapidly expanding interest in interventions to slow myopia progression in children
and teenagers, with the intent of reducing risk of myopia-associated complications later in …

The evidence-basis based on existing myopia control trials along with the supporting
academic literature were reviewed; this informed recommendations on the outcomes …

In this article, we highlight the distinctive features of a feasibility study, identify the main
objectives and guiding questions of a feasibility study, and illustrate the use of these …

Background and Purpose—The modified Rankin Scale (mRS) at 3 months is the most
commonly used primary outcome measure in stroke treatment trials, but it lacks specificity …

Increasing numbers of drugs are being developed for the treatment of multiple sclerosis
(MS). Measurement of relevant outcomes is key for assessing the efficacy of new drugs in …

Music-based interventions (MBIs) show promise for managing symptoms of various brain
disorders. To fully realize the potential of MBIs and dispel the outdated misconception that …

Patient-reported outcomes (PROs) are increasingly used in multiple sclerosis (MS) research
and clinical practice for understanding the effects that the disease and its treatments have on …

Randomised controlled trials often use surrogate endpoints to substitute for a target outcome
(an outcome of direct interest and relevance to trial participants, clinicians, and other …

Acupuncture and related therapies such as moxibustion and transcutaneous electrical nerve
stimulation are often used to manage cancer-related symptoms, but their effectiveness and …

Much of the work developing and testing new instruments for use in rehabilitation research
and practice has occurred in English-speaking countries. Therefore rehabilitation …