Macrolides are among the most widely prescribed broad spectrum antibacterials, particularly
for respiratory infections. It is now recognized that these drugs, in particular azithromycin …

Appearance of alveolar protein-rich edema is an early event in the development of acute
respiratory distress syndrome (ARDS). Alveolar edema in ARDS results from a significant …

BACKGROUND: Chronic rhinosinusitis (CRS) is a common disease with still unclear
pathophysiologic mechanisms. Epithelial tight junctions (TJs) have been shown to be …

Human matrix metalloproteinases (MMPs) belong to the M10 family of the MA clan of
endopeptidases. They are ubiquitarian enzymes, structurally characterized by an active site …

The mammalian airway is lined by a variety of specialized epithelial cells that not only serve
as a physical barrier but also respond to environment-induced damage through the release …

Neurotoxicity is a common side effect of chemotherapy treatment, with unclear molecular
mechanisms. Clinical studies suggest that the most frequent neurotoxic adverse events …

Purpose The effect of air pollution-related particulate matter (PM) on epithelial barrier
function and tight junction (TJ) expression in human nasal mucosa has not been studied to …

The association between pulmonary sequelae and markers of disease severity, as well as
pro-fibrotic mediators, were studied in 108 patients 3 months after hospital admission for …

This paper describes a new human alveolar epithelial cell line (hAELVi-human Alveolar
Epithelial Lentivirus immortalized) with type I-like characteristics and functional tight …

Objective To evaluate the expression of matrix metalloproteinase 9 (MMP9) and
transglutaminase 2 (TG2) in different forms of dry eye. Design Case control study …