Background Bioactivity and self-assembly are two important properties of peptides. Over the
past several decades, rapid advances have been made in the application of bioactive …

Self-assembly is the most suitable approach to obtaining peptide-based materials on the
nano-and mesoscopic scales. Applications span from peptide drugs for personalized …

Peptide self-assembly is the process by which peptide molecules aggregate into low
dimensional (1D, 2D) or 3D ordered materials with potential applications ranging from drug …

Among the various factors controlling the amyloid aggregation process, the influences of
ions on the aggregation rate and the resulting structures are important aspects to consider …

The formation of amyloid fibrils is a complex phenomenon that remains poorly understood at
the atomic scale. Herein, we perform extended unbiased all-atom simulations in explicit …

Synthetic peptides that self-assemble into cross-β fibrils are versatile building blocks for
engineered biomaterials due to their modularity and biocompatibility, but their structural and …

An understanding of how the amino acid sequence affects the interaction of peptides with
lipid membranes remains mostly unknown. This type of knowledge is required to rationalize …

Due to the lack of blood vessels, nerves and lymphatic vessels, the capacity of articular
cartilage to heal is extremely limited. Once damaged, it is urgent for articular cartilage to …

Amphipathic peptides can cause biological membranes to leak either by dissolving their
lipid content via a detergent-like mechanism or by forming pores on the membrane surface …

One of the most desirable properties that biomaterials designed for tissue engineering or
drug delivery applications should fulfill is biodegradation and resorption without toxicity …