Pathophysiology of COVID-19-associated acute kidney injury

M Legrand, S Bell, L Forni, M Joannidis… - Nature Reviews …, 2021 - nature.com
Although respiratory failure and hypoxaemia are the main manifestations of COVID-19,
kidney involvement is also common. Available evidence supports a number of potential …

Trained immunity—basic concepts and contributions to immunopathology

J Ochando, WJM Mulder, JC Madsen… - Nature Reviews …, 2023 - nature.com
Trained immunity is a functional state of the innate immune response and is characterized
by long-term epigenetic reprogramming of innate immune cells. This concept originated in …

Nitric oxide signalling in kidney regulation and cardiometabolic health

M Carlström - Nature reviews nephrology, 2021 - nature.com
The prevalence of cardiovascular and metabolic disease coupled with kidney dysfunction is
increasing worldwide. This triad of disorders is associated with considerable morbidity and …

Impact of the COVID-19 pandemic on the kidney community: lessons learned and future directions

D Geetha, A Kronbichler, M Rutter, D Bajpai… - Nature Reviews …, 2022 - nature.com
Abstract The coronavirus disease 2019 (COVID-19) pandemic has disproportionately
affected patients with kidney disease, causing significant challenges in disease …

The impact of population ageing on the burden of chronic kidney disease

NC Chesnaye, A Ortiz, C Zoccali, VS Stel… - Nature Reviews …, 2024 - nature.com
The burden of chronic kidney disease (CKD) and its risk factors are projected to rise in
parallel with the rapidly ageing global population. By 2050, the prevalence of CKD category …

Antibody response to mRNA SARS-CoV-2 vaccine among dialysis patients—a prospective cohort study

T Agur, N Ben-Dor, S Goldman… - Nephrology Dialysis …, 2021 - academic.oup.com
Emerging data has established end-stage renal disease (ESRD) as one of the highest risk
comorbidities for severe coronavirus disease 2019 (COVID-19), with short-term mortality …

Pharmacokinetics of oral nirmatrelvir/ritonavir, a protease inhibitor for treatment of COVID‐19, in subjects with renal impairment

SS Toussi, JM Neutel, J Navarro… - Clinical …, 2022 - Wiley Online Library
Nirmatrelvir coadministered with ritonavir is highly efficacious in reducing the risk of
coronavirus disease 2019 (COVID‐19) adverse outcomes among patients at increased risk …

COVID-19-related mortality in kidney transplant and haemodialysis patients: a comparative, prospective registry-based study

E Goffin, A Candellier, P Vart, M Noordzij… - Nephrology Dialysis …, 2021 - academic.oup.com
Abstract Background Coronavirus disease 2019 (COVID-19) has exposed haemodialysis
(HD) patients and kidney transplant (KT) recipients to an unprecedented life-threatening …

Characteristics associated with poor COVID-19 outcomes in individuals with systemic lupus erythematosus: data from the COVID-19 Global Rheumatology Alliance

MF Ugarte-Gil, GS Alarcón, Z Izadi… - Annals of the …, 2022 - ard.bmj.com
Aim To determine characteristics associated with more severe outcomes in a global registry
of people with systemic lupus erythematosus (SLE) and COVID-19. Methods People with …

The RECOVAC immune-response study: the immunogenicity, tolerability, and safety of COVID-19 vaccination in patients with chronic kidney disease, on dialysis, or …

JSF Sanders, FJ Bemelman, AL Messchendorp… - …, 2022 - journals.lww.com
Background. In kidney patients COVID-19 is associated with severely increased morbidity
and mortality. A comprehensive comparison of the immunogenicity, tolerability, and safety of …