Toward biotechnology in space: High-throughput instruments for in situ biological research beyond Earth

F Karouia, K Peyvan, A Pohorille - Biotechnology advances, 2017 - Elsevier
Abstract Space biotechnology is a nascent field aimed at applying tools of modern biology to
advance our goals in space exploration. These advances rely on our ability to exploit in situ …

Impact of Microgravity on Virulence, Antibiotic Resistance and Gene Expression in Beneficial and Pathogenic Microorganisms

M Salavatifar, SM Ahmadi, SD Todorov… - Mini Reviews in …, 2023 - ingentaconnect.com
During space missions, the impact of the space conditions (both microgravity and radiation)
on physiologic and metabolic aspects of the microbiota of astronauts' bodies should be …

Phenotypic diversity of Flo protein family-mediated adhesion in Saccharomyces cerevisiae

SE Van Mulders, E Christianen… - FEMS Yeast …, 2009 - academic.oup.com
The Saccharomyces cerevisiae genome encodes a Flo (flocculin) adhesin family
responsible for cell–cell and cell–surface adherence. In commonly used laboratory strains …

Fungal biotechnology in space: why and how?

M Cortesão, T Schütze, R Marx, R Moeller… - Grand challenges in …, 2020 - Springer
Fungi have been companions of mankind for millennia. Mushrooms inspired our eating
culture, and yeasts and filamentous fungi were developed into highly efficient cell factories …

The Influence of Microgravity on Invasive Growth in Saccharomyces cerevisiae

SE Van Mulders, C Stassen, L Daenen, B Devreese… - Astrobiology, 2011 - liebertpub.com
This study investigates the effects of microgravity on colony growth and the morphological
transition from single cells to short invasive filaments in the model eukaryotic organism …

Enhanced S‐adenosyl‐l‐methionine production in Saccharomyces cerevisiae by spaceflight culture, overexpressing methionine adenosyltransferase and …

Y Huang, X Gou, H Hu, Q Xu, Y Lu… - Journal of applied …, 2012 - academic.oup.com
Abstract Aims: S‐adenosyl‐l‐methionine (SAM) is an important biochemical molecule with
great potential in the pharmacological and chemotherapeutic fields. In this study, our aims …

Physical forces modulate oxidative status and stress defense meditated metabolic adaptation of yeast colonies: Spaceflight and microgravity simulations

TG Hammond, PL Allen, MA Gunter, J Chiang… - … Science and Technology, 2018 - Springer
Baker's yeast (Saccharomyces cerevisiae) has broad genetic homology to human cells.
Although typically grown as 1-2mm diameter colonies under certain conditions yeast can …

The growth behavior of the model eukaryotic yeast Saccharomyces cerevisiae in microgravity

RG Willaert - Current Biotechnology, 2013 - ingentaconnect.com
Saccharomyces cerevisiae is an eukaryotic model organism that has been used for space
biology research. Microgravity is a tool to study yeast mechanobiology by removing the …

Yeast in space

TG Hammond, HH Birdsall - Handbook of Space Pharmaceuticals, 2022 - Springer
Humans and yeast have traveled together through a long history of terrestrial explorations
and will continue to do so as mankind explores space. Candida species of yeast accompany …

Saccharomyces cerevisiae as a Model for Space Biology

SD Halbandge, PB Vidyasagar… - Yeast Diversity in Human …, 2017 - Springer
Manned spaceflight continues to be in the agenda of most of the countries involved in space
research. Development of human settlements in planets and sustainable space ecosystems …