Emerging and reemerging infectious diseases: global trends and new strategies for their prevention and control

S Wang, W Li, Z Wang, W Yang, E Li, X Xia… - … and Targeted Therapy, 2024 - nature.com
To adequately prepare for potential hazards caused by emerging and reemerging infectious
diseases, the WHO has issued a list of high-priority pathogens that are likely to cause future …

Human microglial models to study host–virus interactions

RE McMillan, E Wang, AF Carlin, NG Coufal - Experimental neurology, 2023 - Elsevier
Microglia, the resident macrophage of the central nervous system, are increasingly
recognized as contributing to diverse aspects of human development, health, and disease …

Wulfenioidins D–N, Structurally Diverse Diterpenoids with Anti-Zika Virus Activity Isolated from Orthosiphon wulfenioides

WC Tu, YX Huang, B Li, YJ Jiang… - Journal of Natural …, 2023 - ACS Publications
Eleven diterpenoids, wulfenioidins D–N (1–11), classified into five distinct carbon skeletons
with one unreported framework, and four modified abietane diterpenoids were isolated from …

Vitamin D modulates expression of antimicrobial peptides and proinflammatory cytokines to restrict Zika virus infection in macrophages

GJ Fernandez, JM Ramírez-Mejía, JA Castillo… - International …, 2023 - Elsevier
Although the impact of Zika virus (ZIKV) infection on human health has been well
documented, we still have no vaccine or effective treatment. This fact highlights the …

SCARPET: site-specific quantification of methylated and nonmethylated adenosines reveals m6A stoichiometry

AH Mirza, Y Bram, RE Schwartz, SR Jaffrey - RNA, 2024 - rnajournal.cshlp.org
m6A has different stoichiometry at different positions in different mRNAs. However, the exact
stoichiometry of m6A is difficult to measure. Here, we describe SCARPET (site-specific …

Detection and persistence of Zika virus in body fluids and associated factors: a prospective cohort study

GA Calvet, EO Kara, CHA Bôtto-Menezes… - Scientific Reports, 2023 - nature.com
This study aimed to analyze the detection and duration of the Zika virus (ZIKV) in plasma,
urine, saliva, sweat, rectal swabs, vaginal secretions, breast milk, and semen and to explore …

AMFR-mediated Flavivirus NS2A ubiquitination subverts ER-phagy to augment viral pathogenicity

L Zhang, H Wang, C Han, Q Dong, J Yan… - Nature …, 2024 - nature.com
Flaviviruses strategically utilize the endoplasmic reticulum (ER) in their replication cycles.
However, the role of ER autophagy (ER-phagy) in viral replication process remains poorly …

The fate of neuronal synapse homeostasis in aging, infection, and inflammation

C Tacke, P Landgraf, DC Dieterich… - American Journal of …, 2024 - journals.physiology.org
Neuroplasticity is the brain's ability to reorganize and modify its neuronal connections in
response to environmental stimuli, experiences, learning, and disease processes. This …

Zika virus: Antiviral immune response, inflammation, and cardiotonic steroids as antiviral agents

JM de Sales-Neto, DCM Carvalho… - International …, 2024 - Elsevier
Zika virus (ZIKV) is a mosquito-borne virus first reported from humans in Nigeria in 1954.
The first outbreak occurred in Micronesia followed by an outbreak in French Polynesia and …

[HTML][HTML] YIPF5 (p. W218R) mutation induced primary microcephaly in rabbits

X Liu, J Yang, Z Li, R Liu, X Wu, Z Zhang, L Lai… - Neurobiology of …, 2023 - Elsevier
Primary microcephaly (PMCPH) is a rare autosomal recessive neurodevelopmental disorder
with a global prevalence of PMCPH ranging from 0.0013% to 0.15%. Recently, a …