The adaptation of adenoviruses as gene delivery tools has resulted in the development of
high-capacity adenoviral vectors (HC-AdVs), also known, helper-dependent or “gutless” …

Adenoviruses have been characterized extensively since their initial description in the early
1950s (Hillemann & Werner, 1954; Rowe et al., 1953) and there is now a panoply of …

Efficient retrograde access to projection neurons for the delivery of sensors and effectors
constitutes an important and enabling capability for neural circuit dissection. Such an …

Deciphering how neural circuits are anatomically organized with regard to input and output
is instrumental in understanding how the brain processes information. For example, locus …

The basolateral amygdala (BLA) mediates associative learning for both fear and reward.
Accumulating evidence supports the notion that different BLA projections distinctly alter …

Dopamine modulates medial prefrontal cortex (mPFC) activity to mediate diverse
behavioural functions,; however, the precise circuit computations remain unknown. One …

Appetite suppression occurs after a meal and in conditions when it is unfavourable to eat,
such as during illness or exposure to toxins. A brain region proposed to play a role in …

Orchestrating appropriate behavioral responses in the face of competing signals that predict
either rewards or threats in the environment is crucial for survival. The basolateral nucleus of …

Social memory—the ability to recognize and remember familiar conspecifics—is critical for
the survival of an animal in its social group,. The dorsal CA2 (dCA2),–and ventral CA1 …

Slow, controlled breathing has been used for centuries to promote mental calming, and it is
used clinically to suppress excessive arousal such as panic attacks. However, the …