The emerging mechanisms and functions of microautophagy

L Wang, DJ Klionsky, HM Shen - Nature reviews Molecular cell biology, 2023 - nature.com
Abstract 'Autophagy'refers to an evolutionarily conserved process through which cellular
contents, such as damaged organelles and protein aggregates, are delivered to lysosomes …

Oxidative stress in human pathology and aging: molecular mechanisms and perspectives

YA Hajam, R Rani, SY Ganie, TA Sheikh, D Javaid… - Cells, 2022 - mdpi.com
Reactive oxygen and nitrogen species (RONS) are generated through various endogenous
and exogenous processes; however, they are neutralized by enzymatic and non-enzymatic …

MIROs and DRP1 drive mitochondrial-derived vesicle biogenesis and promote quality control

T König, H Nolte, MJ Aaltonen, T Tatsuta, M Krols… - Nature cell …, 2021 - nature.com
Mitochondrial-derived vesicles (MDVs) are implicated in diverse physiological processes—
for example, mitochondrial quality control—and are linked to various neurodegenerative …

[HTML][HTML] Mitochondrial degradation: Mitophagy and beyond

L Uoselis, TN Nguyen, M Lazarou - Molecular cell, 2023 - cell.com
Mitochondria are central hubs of cellular metabolism that also play key roles in signaling
and disease. It is therefore fundamentally important that mitochondrial quality and activity …

Molecular mechanisms of mitochondrial dynamics

LC Tábara, M Segawa, J Prudent - Nature Reviews Molecular Cell …, 2024 - nature.com
Mitochondria not only synthesize energy required for cellular functions but are also involved
in numerous cellular pathways including apoptosis, calcium homoeostasis, inflammation …

VPS13D bridges the ER to mitochondria and peroxisomes via Miro

A Guillén-Samander, M Leonzino, MG Hanna IV… - Journal of Cell …, 2021 - rupress.org
Mitochondria, which are excluded from the secretory pathway, depend on lipid transport
proteins for their lipid supply from the ER, where most lipids are synthesized. In yeast, the …

Mitochondria shed their outer membrane in response to infection-induced stress

X Li, J Straub, TC Medeiros, C Mehra, F den Brave… - Science, 2022 - science.org
INTRODUCTION Mitochondria are dynamic organelles that coordinate many cellular
functions that are essential for life, including diverse metabolic processes, cell division and …

Completion of mitochondrial division requires the intermembrane space protein Mdi1/Atg44

OM Connor, SK Matta, JR Friedman - Journal of Cell Biology, 2023 - rupress.org
Mitochondria are highly dynamic double membrane–bound organelles that maintain their
shape in part through fission and fusion. Mitochondrial fission is performed by a dynamin …

Structure and function of mitochondria‐associated endoplasmic reticulum membranes (MAMs) and their role in cardiovascular diseases

Y Luan, Y Luan, RX Yuan, Q Feng… - … Medicine and Cellular …, 2021 - Wiley Online Library
Abnormal function of suborganelles such as mitochondria and endoplasmic reticulum often
leads to abnormal function of cardiomyocytes or vascular endothelial cells and …

Muscle mitochondrial transplantation can rescue and maintain cellular homeostasis

D Bhattacharya, MB Slavin… - American Journal of …, 2023 - journals.physiology.org
Mitochondria control cellular functions through their metabolic role. Recent research that has
gained considerable attention is their ability to transfer between cells. This has the potential …