[HTML][HTML] Phage therapy: From biological mechanisms to future directions

SA Strathdee, GF Hatfull, VK Mutalik, RT Schooley - Cell, 2023 - cell.com
Increasing antimicrobial resistance rates have revitalized bacteriophage (phage) research,
the natural predators of bacteria discovered over 100 years ago. In order to use phages …

Interactions between bacterial and phage communities in natural environments

A Chevallereau, BJ Pons, S van Houte… - Nature Reviews …, 2022 - nature.com
We commonly acknowledge that bacterial viruses (phages) shape the composition and
evolution of bacterial communities in nature and therefore have important roles in ecosystem …

IMG/VR v4: an expanded database of uncultivated virus genomes within a framework of extensive functional, taxonomic, and ecological metadata

AP Camargo, S Nayfach, IMA Chen… - Nucleic acids …, 2023 - academic.oup.com
Viruses are widely recognized as critical members of all microbiomes. Metagenomics
enables large-scale exploration of the global virosphere, progressively revealing the …

VirSorter2: a multi-classifier, expert-guided approach to detect diverse DNA and RNA viruses

J Guo, B Bolduc, AA Zayed, A Varsani… - Microbiome, 2021 - Springer
Background Viruses are a significant player in many biosphere and human ecosystems, but
most signals remain “hidden” in metagenomic/metatranscriptomic sequence datasets due to …

Metagenomic compendium of 189,680 DNA viruses from the human gut microbiome

S Nayfach, D Páez-Espino, L Call, SJ Low… - Nature …, 2021 - nature.com
Bacteriophages have important roles in the ecology of the human gut microbiome but are
under-represented in reference databases. To address this problem, we assembled the …

CheckV assesses the quality and completeness of metagenome-assembled viral genomes

S Nayfach, AP Camargo, F Schulz… - Nature …, 2021 - nature.com
Millions of new viral sequences have been identified from metagenomes, but the quality and
completeness of these sequences vary considerably. Here we present CheckV, an …

[HTML][HTML] Massive expansion of human gut bacteriophage diversity

LF Camarillo-Guerrero, A Almeida, G Rangel-Pineros… - Cell, 2021 - cell.com
Bacteriophages drive evolutionary change in bacterial communities by creating gene flow
networks that fuel ecological adaptions. However, the extent of viral diversity and its …

Soil viral diversity, ecology and climate change

JK Jansson, R Wu - Nature Reviews Microbiology, 2023 - nature.com
Soil viruses are highly abundant and have important roles in the regulation of host dynamics
and soil ecology. Climate change is resulting in unprecedented changes to soil ecosystems …

Phyllosphere microbiome

R Sohrabi, BC Paasch, JA Liber… - Annual review of plant …, 2023 - annualreviews.org
The aboveground parts of terrestrial plants are colonized by a variety of microbes that
collectively constitute the phyllosphere microbiota. Decades of pioneering work using …

Phage diversity, genomics and phylogeny

MB Dion, F Oechslin, S Moineau - Nature Reviews Microbiology, 2020 - nature.com
Recent advances in viral metagenomics have enabled the rapid discovery of an
unprecedented catalogue of phages in numerous environments, from the human gut to the …