Many studies show that glucose metabolism in epileptic brain areas can be impaired.
Energy is crucial to maintain normal brain function, including ion and neurotransmitter …

Epilepsy is a common neurological disease in both humans and domestic dogs, making
dogs an ideal translational model of epilepsy. In both species, epilepsy is a complex brain …

OBJECTIVE To assess the effect of oral cannabidiol (CBD) administration in addition to
conventional antiepileptic treatment on seizure frequency in dogs with idiopathic epilepsy …

Maintenance of bile acid (BA) homeostasis is essential to achieve their physiologic functions
and avoid their toxic effects. The marked differences in BA composition between preclinical …

Epilepsy is a challenging multifactorial disorder with a complex genetic background. Our
current understanding of the pathophysiology and treatment of epilepsy has substantially …

Background Seizure emergencies (ie, status epilepticus [SE] and cluster seizures [CS]), are
common challenging disorders with complex pathophysiology, rapidly progressive drug …

Drug resistance continues to be a major clinical problem in the therapeutic management of
canine epilepsies with substantial implications for quality of life and survival times …

The fourth edition of Clinical Medicine of the Dog and Cat remains the most extensively
illustrated and practical small animal veterinary textbook on the market. It continues and …

Psychiatric and cognitive comorbidities have been known to play a major role in human
epilepsy for a long time. People with epilepsy (PWE) frequently express signs of varying …

Phenobarbital (PB) is one of the most important antiseizure drugs (ASDs) to treat canine
idiopathic epilepsy (IE). The effect of PB on the taxonomic changes in gastrointestinal …