SARS-CoV-2 reservoir in post-acute sequelae of COVID-19 (PASC)

AD Proal, MB VanElzakker, S Aleman, K Bach… - Nature …, 2023 - nature.com
Millions of people are suffering from Long COVID or post-acute sequelae of COVID-19
(PASC). Several biological factors have emerged as potential drivers of PASC pathology …

Viral persistence in children infected with SARS-CoV-2: current evidence and future research strategies

D Buonsenso, L Martino, R Morello, F Mariani… - The Lancet …, 2023 - thelancet.com
Summary In this Personal View, we discuss current knowledge on SARS-CoV-2 RNA or
antigen persistence in children infected with SARS-CoV-2. Based on the evidence that the …

Deep phenotyping of post-infectious myalgic encephalomyelitis/chronic fatigue syndrome

B Walitt, K Singh, SR LaMunion, M Hallett… - Nature …, 2024 - nature.com
Post-infectious myalgic encephalomyelitis/chronic fatigue syndrome (PI-ME/CFS) is a
disabling disorder, yet the clinical phenotype is poorly defined, the pathophysiology is …

[HTML][HTML] Association of COVID-19 with respiratory syncytial virus (RSV) infections in children aged 0–5 years in the USA in 2022: a multicentre retrospective cohort …

L Wang, PB Davis, N Berger, DC Kaelber… - Family medicine and …, 2023 - ncbi.nlm.nih.gov
Objective To investigate whether COVID-19 infection was associated with increased risk for
incident respiratory syncytial virus (RSV) infections and associated diseases among young …

Innate and adaptive immunity during SARS-CoV-2 infection: biomolecular cellular markers and mechanisms

B Brown, V Ojha, I Fricke, SA Al-Sheboul, C Imarogbe… - Vaccines, 2023 - mdpi.com
The coronavirus 2019 (COVID-19) pandemic was caused by a positive sense single-
stranded RNA (ssRNA) severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …

B cell phylogenetics in the single cell era

KB Hoehn, SH Kleinstein - Trends in Immunology, 2024 - cell.com
The widespread availability of single-cell RNA sequencing (scRNA-seq) has led to the
development of new methods for understanding immune responses. Single-cell …

Challenges and opportunities in long COVID research

RE Hamlin, CA Blish - Immunity, 2024 - cell.com
Long COVID (LC) is a condition in which patients do not fully recover from the initial SARS-
CoV-2 infection but rather have persistent or new symptoms for months to years following …

The persistence of SARS-CoV-2 in tissues and its association with long COVID symptoms: a cross-sectional cohort study in China

W Zuo, D He, C Liang, S Du, Z Hua, Q Nie… - The Lancet Infectious …, 2024 - thelancet.com
Background Growing evidence suggests that symptoms associated with post-COVID-19
condition (also known as long COVID) can affect multiple organs and systems in the human …

Language model-based B cell receptor sequence embeddings can effectively encode receptor specificity

M Wang, J Patsenker, H Li, Y Kluger… - Nucleic acids …, 2024 - academic.oup.com
High throughput sequencing of B cell receptors (BCRs) is increasingly applied to study the
immense diversity of antibodies. Learning biologically meaningful embeddings of BCR …

Tonsils are major sites of persistence of SARS-CoV-2 in children

TM Lima, RB Martins, CS Miura, MVO Souza… - Microbiology …, 2023 - Am Soc Microbiol
In the present study, we show that SARS-CoV-2 can infect palatine tonsils, adenoids, and
secretions in children without symptoms of COVID-19, with no history of recent upper airway …