Polydopamine nanoparticle-based combined chemotherapy and photothermal therapy for the treatment of liver cancer

M Emanet, MC Lefevre, MC Ceccarelli… - … Applied Materials & …, 2024 - ACS Publications
Polydopamine nanoparticles (PDA NPs) are proposed as an anti-cancer tool against
hepatocellular carcinoma through the combination of near-infrared (NIR)-mediated …

Nanotechnology in the diagnostic and therapy of hepatocellular carcinoma

F Graur, A Puia, EI Mois, S Moldovan, A Pusta… - Materials, 2022 - mdpi.com
Hepatocellular carcinoma is the most common liver malignancy and is among the top five
most common cancers. Despite the progress of surgery and chemotherapy, the results are …

Preparation, characterization, cytotoxicity and pharmacokinetics of niosomes containing gemcitabine: In vitro, in vivo, and simulation studies

M Barani, MR Hajinezhad, F Zargari, S Shahraki… - Journal of Drug Delivery …, 2023 - Elsevier
Novel niosomes including cholesterol, Span (60), Tween (60), and gemcitabine (GEM) have
been developed via film hydration approach and characterized via in vitro, in vivo, and in …

FTO-mediated LINC01134 stabilization to promote chemoresistance through miR-140-3p/WNT5A/WNT pathway in PDAC

J Lu, Y Yang, X Liu, X Chen, W Song, Z Liu - Cell Death & Disease, 2023 - nature.com
Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive cancer most frequently
detected at an advanced stage that limits treatment options to systemic chemotherapy, which …

Hypoxia-alleviated nanoplatform to enhance chemosensitivity and sonodynamic effect in pancreatic cancer

J Chen, Y Bao, Y Song, C Zhang, F Qiu, Y Sun, L Xin… - Cancer Letters, 2021 - Elsevier
Pancreatic cancer is a severe disease that threatens human health. The hypoxic tumor
microenvironment in pancreatic cancer leads to resistance to conventional therapies and …

[HTML][HTML] Design, Synthesis, Characterization, and Cytotoxicity of New Pyrazolylmethylene-2-thioxoimidazolidin-4-one Derivatives towards Androgen-Sensitive LNCaP …

MA El-Atawy, R Kebeish, ARZ Almotairy, AZ Omar - Biomolecules, 2024 - mdpi.com
A new class of pyrazolylmethylene-2-thioxoimidazolidin-4-one derivatives 3a–p were
rationally designed and synthesized with the aim of exploring their potential as treatments …

[HTML][HTML] Gastroprotective, hepatoprotective, and nephroprotective effects of thymol against the adverse effects of acetylsalicylic acid in rats: Biochemical and …

SMA El-Sheikh, HM Bahaa, AAA Galal… - Saudi Journal of …, 2022 - Elsevier
Acetylsalicylic acid (Aspirin) has been used for a long time as an antipyretic and analgesic.
Nevertheless, aspirin use is associated with severe morbidity and death because of its …

Could cisplatin loading on biosynthesized silver nanoparticles improve its therapeutic efficacy on human prostate cancer cell line and reduce its in vivo nephrotoxic …

SMA El-Sheikh, N Edrees, H El-Sayed… - … Trace Element Research, 2021 - Springer
Nanotechnology is a possible solution to the drawbacks of cancer therapy because it
decreases the clinical side effects of chemotherapeutic drugs and increases their clinical …

Gemcitabine and synthesized silver nanoparticles impact on chemically induced hepatocellular carcinoma in male rats

MR Mohamed, SA Osman, AA Hassan… - International …, 2024 - journals.sagepub.com
Objective: Gemcitabine (GEM) is a deoxycytidine analog chemotherapeutic drug widely
used to treat many cancers. Silver nanoparticles (AgNPs) are important nanomaterials used …

[HTML][HTML] Synergistic effect of baculovirus-mediated endostatin and angiostatin combined with gemcitabine in hepatocellular carcinoma

Y Ji, H Fan, M Yang, C Bai, W Yang… - Biological and …, 2022 - jstage.jst.go.jp
Anti-angiogenic gene therapy is a promising strategy in treating cancer. Endostatin and
angiostatin are widely used in tumor anti-angiogenesis therapy. Our previous studies have …