Physical properties of nanoparticles that result in improved cancer targeting

R Zein, W Sharrouf, K Selting - Journal of Oncology, 2020 - Wiley Online Library
The therapeutic efficacy of drugs is dependent upon the ability of a drug to reach its target,
and drug penetration into tumors is limited by abnormal vasculature and high interstitial …

Targeted delivery methods for anticancer drugs

VV Veselov, AE Nosyrev, L Jicsinszky, RN Alyautdin… - Cancers, 2022 - mdpi.com
Simple Summary The current main technological strategies for the delivery of anticancer
drugs are discussed herein. This comprehensive review may help researchers design …

Lignin, lipid, protein, hyaluronic acid, starch, cellulose, gum, pectin, alginate and chitosan-based nanomaterials for cancer nanotherapy: Challenges and opportunities

CC Carrion, M Nasrollahzadeh, M Sajjadi… - International Journal of …, 2021 - Elsevier
Although nanotechnology-driven drug delivery systems are relatively new, they are rapidly
evolving since the nanomaterials are deployed as effective means of diagnosis and delivery …

Pectin polymers for colon-targeted antitumor drug delivery

M Khotimchenko - International journal of biological macromolecules, 2020 - Elsevier
The use of chemotherapeutic drugs in the treatment of malignant tumors is always
associated with the severe side effects negatively affecting all organs and systems in human …

Physical properties of nanoparticles do matter

TM Kiio, S Park - Journal of Pharmaceutical Investigation, 2021 - Springer
Abstract Background Nanoparticles (NPs) have been used to enhance pharmaceutical
properties of drugs, including cell/tissue penetration, selective biodistribution, circulation half …

Polysaccharide-based formulations as potential carriers for pulmonary delivery–a review of their properties and fates

SA Valente, LM Silva, GR Lopes, B Sarmento… - Carbohydrate …, 2022 - Elsevier
Polysaccharides can be elite carriers for therapeutic molecules due to their versatility and
low probability to trigger toxicity and immunogenic responses. Local and systemic therapies …

The roles of polysaccharides in carp farming: A review

KW Goh, Z Abdul Kari, W Wee, H Van Doan… - Animals, 2023 - mdpi.com
Simple Summary Disease outbreaks pose a major challenge for farmers in sustaining carp
farming. Antibiotics and chemicals are the conventional solutions to improve carp growth …

Encapsulation of honokiol into self-assembled pectin nanoparticles for drug delivery to HepG2 cells

Y Zhang, T Chen, P Yuan, R Tian, W Hu, Y Tang… - Carbohydrate …, 2015 - Elsevier
Self-assembled pectin nanoparticles was prepared and evaluated for delivering the
hydrophobic drug, honokiol (HK), to HepG2 cells. These hydrophobic drug-loaded …

Pectin-tannic acid nano-complexes promote the delivery and bioactivity of drugs in pancreatic cancer cells

SS Chauhan, AB Shetty, E Hatami, P Chowdhury… - Pharmaceutics, 2020 - mdpi.com
Pancreatic cancer (PanCa) is a lethal disease. Conventional chemotherapies for PanCa
offer severe systemic toxicities. Thus, the development of a successful nanomedicine-based …

Structural characterization and rheological properties of a pectin with anti-constipation activity from the roots of Arctium lappa L

K Li, L Zhu, H Li, Y Zhu, C Pan, X Gao, W Liu - Carbohydrate polymers, 2019 - Elsevier
Abstract A new pectin (ALP-2) was extracted from the roots of Arctium lappa L. with the
molecular weight of 1.84× 10 6 Da. ALP-2 was composed of rhamnose, glucuronic acid …