Cancer cells undergo metabolic alterations to meet the immense demand for energy,
building blocks, and redox potential. Tumors show glucose-avid and lactate-secreting …

The dysregulation of the splicing process has emerged as a novel hallmark of metabolic and
tumor pathologies. In breast cancer (BCa), which represents the most diagnosed cancer …

CD73, a cell surface‐bound nucleotidase, facilitates extracellular adenosine formation by
hydrolyzing 5′‐AMP to adenosine. Several studies have shown that CD73 plays an …

Background Invasive lobular carcinoma (ILC) treatment is similar to invasive ductal
carcinoma (IDC; now invasive carcinoma-no special type, IBC-NST), based on its intrinsic …

Simple Summary bHLH transcription factors control a variety of functions during
development and disease. Atoh8 is one such bHLH factor with unique characteristics in the …

Background Aberrant glycosylation, catalyzed by the specific glycosyltransferase, is one of
the dominant features of cancers. Among the glycosyltransferase subfamilies …

Thyroid hormone receptor interactor 13 (TRIP13), an AAA-ATPase, participates in the
development of many cancers. This study explores the function of TRIP13 and synergistic …

Small GTPases regulate multiple important cellular behaviors and their activities are strictly
controlled by a mass of regulators. The dysfunction or abnormal expression of small …

Glioblastoma (GBM) is the most malignant tumor in human brain. High invasiveness of this
tumor is the main reason causing treatment failure and recurrence. Previous study has found …

Objective The main goal of the present research is to explore the potential link of body mass
index (BMI) with different survival metrics in breast cancer patients. Our aim is to offer the …