β-Lactams against the Fortress of the Gram-Positive Staphylococcus aureus Bacterium

JF Fisher, S Mobashery - Chemical reviews, 2020 - ACS Publications
The biological diversity of the unicellular bacteria—whether assessed by shape, food,
metabolism, or ecological niche—surely rivals (if not exceeds) that of the multicellular …

Regulating the intersection of metabolism and pathogenesis in gram‐positive bacteria

AR Richardson, GA Somerville… - Metabolism and …, 2015 - Wiley Online Library
For prototrophic bacteria, central metabolism (ie, glycolysis, the pentose phosphate
pathway, and the Krebs cycle) supplies the 13 biosynthetic intermediates necessary to …

The antipsychotic olanzapine interacts with the gut microbiome to cause weight gain in mouse

AP Morgan, JJ Crowley, RJ Nonneman… - PloS one, 2014 - journals.plos.org
The second-generation antipsychotic olanzapine is effective in reducing psychotic
symptoms but can cause extreme weight gain in human patients. We investigated the role of …

Cannabidiol is an effective helper compound in combination with bacitracin to kill Gram-positive bacteria

CS Wassmann, P Højrup, JK Klitgaard - Scientific reports, 2020 - nature.com
The cannabinoid cannabidiol (CBD) is characterised in this study as a helper compound
against resistant bacteria. CBD potentiates the effect of bacitracin (BAC) against Gram …

[HTML][HTML] Virulence alterations in staphylococcus aureus upon treatment with the sub-inhibitory concentrations of antibiotics

J Chen, H Zhou, J Huang, R Zhang, X Rao - Journal of advanced research, 2021 - Elsevier
Background The treatment of patients with Staphylococcus aureus infections mainly relies
on antistaphylococcal regimens that are established with effective antibiotics. In antibiotic …

Interplay between Mutations and Efflux in Drug Resistant Clinical Isolates of Mycobacterium tuberculosis

D Machado, TS Coelho, J Perdigao, C Pereira… - Frontiers in …, 2017 - frontiersin.org
Numerous studies show efflux as a universal bacterial mechanism contributing to antibiotic
resistance and also that the activity of the antibiotics subject to efflux can be enhanced by …

Analysis of carbohydrates and glycoconjugates by matrix‐assisted laser desorption/ionization mass spectrometry: An update for 2013–2014

DJ Harvey - Mass Spectrometry Reviews, 2018 - Wiley Online Library
This review is the eighth update of the original article published in 1999 on the application of
Matrix‐assisted laser desorption/ionization mass spectrometry (MALDI) mass spectrometry …

Type IV Pilus-Mediated Inhibition of Acinetobacter baumannii Biofilm Formation by Phenothiazine Compounds

N Vo, BS Sidner, Y Yu, KH Piepenbrink - Microbiology Spectrum, 2023 - Am Soc Microbiol
Infections by pathogenic Acinetobacter species represent a significant burden on the health
care system, despite their relative rarity, due to the difficulty of treating infections through oral …

Cupressus sempervirens Essential Oil: Exploring the Antibacterial Multitarget Mechanisms, Chemcomputational Toxicity Prediction, and Safety Assessment in …

S Akermi, S Smaoui, K Elhadef, M Fourati, N Louhichi… - Molecules, 2022 - mdpi.com
Nowadays, increasing interest has recently been given to the exploration of new food
preservatives to avoid foodborne outbreaks or food spoilage. Likewise, new compounds that …

The regulatory effects of second-generation antipsychotics on lipid metabolism: Potential mechanisms mediated by the gut microbiota and therapeutic implications

H Chen, T Cao, B Zhang, H Cai - Frontiers in Pharmacology, 2023 - frontiersin.org
Second-generation antipsychotics (SGAs) are the mainstay of treatment for schizophrenia
and other neuropsychiatric diseases but cause a high risk of disruption to lipid metabolism …