Pigs have substantial potential as biomedical models for studying human developmental
processes, congenital diseases, and pathogen response mechanisms in addition to utility as …

Water availability is a major factor constraining humanity's ability to meet the future food and
energy needs of a growing and increasingly affluent human population. Water plays an …

The world demand for animal-based food products is anticipated to increase by 70% by
2050. Meeting this demand in a way that has a minimal impact on the environment will …

The pig is an omnivorous, monogastric species with many advantages to serve as an animal
model for human diseases. There are very high similarities to humans in anatomy and …

While CRISPR/Cas9 technology has proven to be a valuable system to generate gene-
targeted modified animals in several species, this tool has been scarcely reported in farm …

Targeted modification of the pig genome can be challenging. Recent applications of the
CRISPR/Cas9 system hold promise for improving the efficacy of genome editing. When a …

Sentience–the ability to feel, perceive and experience–is central to the animal welfare
debate as it raises the question of whether animals experience suffering in life and death …

Laboratory animal models play an important role in the study of human diseases. Using
appropriate animals is critical not only for basic research but also for the development of …

Genetically modified animals are vital for gaining a proper understanding of disease
mechanisms. Mice have long been the mainstay of basic research into a wide variety of …

Comparative medicine is founded on the concept that other animal species share
physiological, behavioral, or other characteristics with humans. Over 2,400 years ago it was …