T cell-mediated beta cell destruction: autoimmunity and alloimmunity in the context of type 1 diabetes
AL Burrack, T Martinov, BT Fife - Frontiers in endocrinology, 2017 - frontiersin.org
Type 1 diabetes (T1D) results from destruction of pancreatic beta cells by T cells of the
immune system. Despite improvements in insulin analogs and continuous blood glucose …
immune system. Despite improvements in insulin analogs and continuous blood glucose …
iPSC technology‐based regenerative therapy for diabetes
Y Kondo, T Toyoda, N Inagaki… - Journal of diabetes …, 2018 - Wiley Online Library
The directed differentiation of human pluripotent stem cells, such as embryonic stem cells
(hESC s) and induced pluripotent stem cells (hi PSC s), into pancreatic endocrine lineages …
(hESC s) and induced pluripotent stem cells (hi PSC s), into pancreatic endocrine lineages …
[HTML][HTML] Proteomic analysis of decellularized pancreatic matrix identifies collagen V as a critical regulator for islet organogenesis from human pluripotent stem cells
In pancreatic tissue engineering, generating human pancreatic islet organoids from stem
cells has been challenging due mainly to a poor understanding of niches required for …
cells has been challenging due mainly to a poor understanding of niches required for …
Decellularized tissue matrix enhances self-assembly of islet organoids from pluripotent stem cell differentiation
Regenerating human islet organoids from stem cells remains a significant challenge
because of our limited knowledge on cues essential for developing the endocrine organoids …
because of our limited knowledge on cues essential for developing the endocrine organoids …
Generation of insulin‐producing cells from human adipose‐derived mesenchymal stem cells on PVA scaffold by optimized differentiation protocol
The studies have been done on patient‐specific human adipose‐derived from mesenchymal
stem cells (hADSCs) like a series of autologous growth factors and nanofibrous scaffolds …
stem cells (hADSCs) like a series of autologous growth factors and nanofibrous scaffolds …
Generation of insulin-producing cells from human induced pluripotent stem cells on PLLA/PVA nanofiber scaffold
Pancreatic tissue engineering as a therapeutic option for restoring and maintenance of
damaged pancreas function has a special focus to using synthetic Scaffolds. This study was …
damaged pancreas function has a special focus to using synthetic Scaffolds. This study was …
Generation of insulin‐producing cells from human‐induced pluripotent stem cells using a stepwise differentiation protocol optimized with platelet‐rich plasma
Studies on patient‐specific human‐induced pluripotent stem cells (hiPSCs) as well as a
series of autologous growth factors presumably will reveal their many benefits for cell base …
series of autologous growth factors presumably will reveal their many benefits for cell base …
[HTML][HTML] Generation of iPSC-derived insulin-producing cells from patients with type 1 and type 2 diabetes compared with healthy control
MJ Kim, EY Lee, YH You, HK Yang, KH Yoon… - Stem Cell Research, 2020 - Elsevier
For alternative sources of β cells, patient-specific induced pluripotent stem cells (iPSCs)
could be promising, as cells derived from the “self” allow autologous transplantation …
could be promising, as cells derived from the “self” allow autologous transplantation …
[HTML][HTML] Therapeutic approaches for Type 1 Diabetes: Promising cell-based approaches to achieve ultimate success
S Sepyani, S Momenzadeh, S Safabakhsh… - SLAS Discovery, 2023 - Elsevier
Abstract Type 1 Diabetes mellitus (T1DM) is a chronic metabolic disorder characterized by
pancreatic β-cells destruction. Despite substantial advances in T1DM treatment, lifelong …
pancreatic β-cells destruction. Despite substantial advances in T1DM treatment, lifelong …
Comparison of osteogenic differentiation potential of induced pluripotent stem cells and buccal fat pad stem cells on 3D-printed HA/β-TCP collagen-coated scaffolds
S Hashemi, L Mohammadi Amirabad… - Cell and Tissue …, 2021 - Springer
Production of a 3D bone construct with high-yield differentiated cells using an appropriate
cell source provides a reliable strategy for different purposes such as therapeutic screening …
cell source provides a reliable strategy for different purposes such as therapeutic screening …