Managing CNS disease in adults with acute lymphoblastic leukemia

RA Larson - Leukemia & Lymphoma, 2018 - Taylor & Francis
The central nervous system (CNS) is an important site of involvement by acute lymphoblastic
leukemia (ALL) in adults. The prevalence is sufficiently high that prophylactic treatment is …

[HTML][HTML] Risk factors for poor outcome in posterior reversible encephalopathy syndrome: systematic review and meta-analysis

Z Chen, G Zhang, A Lerner, AH Wang… - Quantitative Imaging in …, 2018 - ncbi.nlm.nih.gov
Background The roles of clinical etiology and symptoms, imaging findings and biochemical
parameters in predicting the prognosis of posterior reversible encephalopathy syndrome …

Potential neurotoxicity associated with methotrexate

N Apiraksattayakul, J Jitprapaikulsan, K Sanpakit… - Scientific Reports, 2024 - nature.com
This study aimed to elucidate the incidence and characteristics of neurotoxicity in patients
receiving methotrexate (MTX) treatment. A retrospective analysis was performed using data …

Posterior reversible encephalopathy syndrome in children with acute lymphoblastic leukemia: clinical characteristics, risk factors, course, and outcome of disease

S Anastasopoulou, MA Eriksson… - Pediatric blood & …, 2019 - Wiley Online Library
Background Posterior reversible encephalopathy syndrome (PRES) is a distinct entity with
incompletely known predisposing factors. The aim of this study is to describe the incidence …

[HTML][HTML] Methotrexate‐induced leukoencephalopathy presenting as stroke in the emergency department

MT Cruz‐Carreras, P Chaftari, A Shamsnia… - Clinical case …, 2017 - ncbi.nlm.nih.gov
Discussion High‐dose intrathecal methotrexate has shown to decrease central nervous
system disease or metastasis in childhood acute lymphocytic leukemia and non‐Hodgkin …

Posterior reversible encephalopathy syndrome in children:: A prospective follow-up study

AH Darwish - Journal of child neurology, 2020 - journals.sagepub.com
Aim: To evaluate clinical and radiologic presentation, and neurologic outcome of pediatric
posterior reversible encephalopathy syndrome (PRES). Patients and Methods: The study …

Management and clinical outcome of posterior reversible encephalopathy syndrome in pediatric oncologic/hematologic diseases: a PRES subgroup analysis with a …

M Hun, M Xie, Z She, AS Abdirahman, C Li… - Frontiers in …, 2021 - frontiersin.org
This study investigated the management and clinical outcomes along with associated factors
of posterior reversible encephalopathy syndrome (PRES) in childhood …

Clinical characteristics and outcome of children with relapsed medulloblastoma: a retrospective study at a single center in China

S Du, S Yang, X Zhao, J Xiao, S Ren, S Li… - Journal of Pediatric …, 2018 - journals.lww.com
Relapsed medulloblastoma (MB) has a dire prognosis, and chemotherapy remains the main
therapeutic option. We retrospectively analyzed the clinical characteristics and survival rates …

Neuroimaging of CNS infection in haematological malignancy: important signs and common diagnostic pitfalls

EA Lim, R Gnanadurai, JK Ruffle, H Lee, RF Miller… - Clinical Radiology, 2021 - Elsevier
Patients with haematological malignancy are at increased risk of developing central nervous
system (CNS) infections, which are associated with significant morbidity and mortality …

A case of reversible cerebral vasoconstriction syndrome triggered by high‐dose methotrexate in a boy with lymphoma

X Wang, Y Zhang, H You, T Zhu… - Headache: The Journal …, 2020 - Wiley Online Library
Background Reversible cerebral vasoconstriction syndrome (RCVS) is characterized by
thunderclap headaches and transient segmental cerebral arterial vasoconstriction. Many …